3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression

D Löb, N Lengert, VO Chagin, M Reinhart… - Nature …, 2016 - nature.com
DNA replication dynamics in cells from higher eukaryotes follows very complex but highly
efficient mechanisms. However, the principles behind initiation of potential replication …

[HTML][HTML] The absence of p53 during Human Cytomegalovirus infection leads to decreased UL53 expression, disrupting UL50 localization to the inner nuclear …

MI Kuan, JM O'Dowd, EA Fortunato - Virology, 2016 - Elsevier
Our electron microscopy study (Kuan et al., 2016) found HCMV nuclear capsid egress was
significantly reduced in p53 knockout cells (p53KOs), correlating with inhibited formation of …

Characteristics of metazoan DNA replication origins

JRA Hutchins, A Aze, P Coulombe… - … Recombination, and Repair, 2016 - Springer
DNA replication in metazoan cells initiates at multiple discrete chromosomal sites called
replication origins. Recent genome-wide studies have mapped thousands of origins in …