In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

Abstract Treatment of acute myocardial infarction (AMI) has improved significantly in recent
years, but many patients have adverse left ventricular (LV) remodeling, a maladaptive …

In the infarcted myocardium, necrotic cardiomyocytes release danger signals, activating an
intense inflammatory response. Inflammatory pathways play a crucial role in regulation of a …

Background—The presence of intramyocardial hemorrhage (IMH) in ST-segment–elevation
myocardial infarction patients reperfused by primary percutaneous coronary intervention has …

Background—The immune system orchestrates the repair of infarcted myocardium. Imaging
of the cellular inflammatory response by 18F-fluorodeoxyglucose (18F-FDG) positron …

After acute myocardial infarction, ventricular remodeling is characterized by changes at the
molecular, structural, geometrical and functional level that determine progression to heart …

Background: Immune cell–mediated inflammation is an essential process for mounting a
repair response after myocardial infarction (MI). The sympathetic nervous system is known to …

Background—Emerging evidence indicates that persistent microvascular obstruction (PMO)
is more predictive of major adverse cardiovascular events than myocardial infarct (MI) size …

In experimental myocardial infarction (MI), a rise in cell counts of circulating monocyte
subsets contributes to impaired myocardial healing and to atherosclerotic plaque …

Aims IL-12p35 is a pro-inflammatory cytokine that participates in a variety of inflammatory
diseases. This study aimed to determine whether IL-12 regulates cardiac injury and repair …