DNA methylation provides an attractive possible means for propagating the effects of
environmental inputs during fetal life and impacting subsequent adult mental health, which …

The emerging field of behavioral epigenetics is producing a growing body of evidence that
early life experience and social exposure can alter the way by which genes are marked with …

Abstract Methylation at 5-cytosine (5-mC) is a fundamental epigenetic DNA modification
associated recently with cardiac disease. In contrast, the role of 5-hydroxymethylcytosine (5 …

Glioblastomas exhibit widespread molecular alterations including a highly distorted
epigenome. Here, we resolve genome-wide 5-methylcytosine and 5-hydroxymethylcytosine …

DNA methylation at the 5-position of cytosine (5mC) is an epigenetic modification that
regulates gene expression and cellular plasticity in development and disease. The ten …

Background The most widely utilized approaches for quantifying DNA methylation involve
the treatment of genomic DNA with sodium bisulfite; however, this method cannot distinguish …

We have recently reported that mice born from dams stressed during pregnancy (PRS mice),
in adulthood, have behavioral deficits reminiscent of behaviors observed in schizophrenia …

In recent years, numerous studies of gene regulation mechanisms have emerged in
neuroscience. Epigenetic modifications, described as heritable but reversible changes …

Background Astronauts are exposed to 56 Fe ions that may pose a significant health hazard
during and following prolonged missions in deep space. We showed previously that object …

Background Alzheimer's disease (AD) is the most common form of neurodegenerative
disorder that leads to a decline in cognitive function. In AD, aggregates of amyloid β peptide …