Chromosome Duplication in Saccharomyces cerevisiae
SP Bell, K Labib - Genetics, 2016 - academic.oup.com
The accurate and complete replication of genomic DNA is essential for all life. In eukaryotic
cells, the assembly of the multi-enzyme replisomes that perform replication is divided into …
cells, the assembly of the multi-enzyme replisomes that perform replication is divided into …
Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers
The origin recognition complex (ORC) binds sites from which DNA replication is initiated. We
address ORC binding selectivity in vivo by mapping∼ 52,000 ORC2 binding sites …
address ORC binding selectivity in vivo by mapping∼ 52,000 ORC2 binding sites …
[HTML][HTML] How MCM loading and spreading specify eukaryotic DNA replication initiation sites
O Hyrien - F1000Research, 2016 - ncbi.nlm.nih.gov
DNA replication origins strikingly differ between eukaryotic species and cell types. Origins
are localized and can be highly efficient in budding yeast, are randomly located in early fly …
are localized and can be highly efficient in budding yeast, are randomly located in early fly …
[HTML][HTML] Transcriptionally driven DNA replication program of the human parasite Leishmania major
R Lombraña, A Álvarez, JM Fernández-Justel… - Cell reports, 2016 - cell.com
Faithful inheritance of eukaryotic genomes requires the orchestrated activation of multiple
DNA replication origins (ORIs). Although origin firing is mechanistically conserved, how …
DNA replication origins (ORIs). Although origin firing is mechanistically conserved, how …
How and why multiple MCMs are loaded at origins of DNA replication
Recent work suggests that DNA replication origins are regulated by the number of multiple
mini‐chromosome maintenance (MCM) complexes loaded. Origins are defined by the …
mini‐chromosome maintenance (MCM) complexes loaded. Origins are defined by the …
[HTML][HTML] Emerging roles for Ciz1 in cell cycle regulation and as a driver of tumorigenesis
T Pauzaite, U Thacker, J Tollitt, NA Copeland - Biomolecules, 2016 - mdpi.com
Precise duplication of the genome is a prerequisite for the health and longevity of
multicellular organisms. The temporal regulation of origin specification, replication licensing …
multicellular organisms. The temporal regulation of origin specification, replication licensing …
DNA replication in budding yeast: link between chromatin conformation and kinetics of replication
C Panciatici - 2016 - theses.hal.science
Genetic information carried in the cell nucleus must be faithfully duplicated to be transmitted
to daughter cells during cell division. In order to orchestrate their division, cells go through a …
to daughter cells during cell division. In order to orchestrate their division, cells go through a …
Global analysis of the DNA replication program in S. cerevisiae
A Gispan - 2016 - search.proquest.com
DNA replication is a fundamental cellular process. Regulation of DNA replication is critical
for maintaining genomic integrity. This area is heavily studied, but yet is not well understood …
for maintaining genomic integrity. This area is heavily studied, but yet is not well understood …