Renal hyperparathyroidism (rHPT) is a common complication of chronic kidney disease
characterized by elevated parathyroid hormone levels secondary to derangements in the …

Maintenance of a normal serum phosphate level depends on absorption in the gut,
reabsorption and excretion by the kidney, and the flux between the extracellular and skeletal …

Tertiary hyperparathyroidism is a common cause of hypercalcemia after kidney transplant.
We designed this 12-month, prospective, multicenter, open–label, randomized study to …

The ability to monitor changes in the ionic composition of the extracellular environment is a
crucial feature that has evolved in all living organisms. The cloning and characterization of …

Objective: This randomized controlled multicenter pilot trial was conducted to find robust
estimates for the rates of recurrence of 2 surgical strategies for secondary …

The extracellular calcium-sensing receptor CaSR is expressed in blood vessels where its
role is not completely understood. In this study, we tested the hypothesis that the CaSR …

CKD and CKD-related mineral and bone disorders (CKD-MBDs) are associated with high
cardiovascular and mortality risks. In randomized clinical trials (RCTs), no single drug …

The calcium-sensing receptor (CaSR) was cloned over 20 years ago and functionally
demonstrated to regulate circulating levels of parathyroid hormone by maintaining …

Osteoporosis is a chronic inflammatory condition that is characterized by the loss of bone
mineral density (BMD). The current study was undertaken to evaluate the impact of onion …

Background: Chronic kidney disease-mineral and bone disorders (CKD-MBD) have been
associated with poor health outcomes, including diminished quality and length of life …