Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the
central nervous system (CNS). AQP4 is widely expressed throughout the brain, especially at …

Schizophrenia, a severe and debilitating disorder with a high social burden, affects 1% of
the adult world population. Available therapies are unable to treat all the symptoms, and …

Electroconvulsive therapy (ECT) is a highly effective and rapidly acting treatment for severe
depression. To understand the biological bases of therapeutic response, we examined …

Increasing evidence suggests that motor rehabilitation may delay Parkinson's disease (PD)
progression. Moreover, parallel treatments in animals up-regulate brain-derived …

Neuronal survival depends on multiple factors that comprise a well‐fueled energy
metabolism, trophic input, clearance of toxic substances, appropriate redox environment …

Ancestral stress can program stress sensitivity and health trajectories across multiple
generations. While ancestral stress is uncontrollable to the filial generations, it is critical to …

Background: The survival of motor neurons is dependent upon neurotrophic factors both
during childhood and adolescence and during adult life. In disease conditions, such as in …

Background Brain-derived neurotrophic factor (BDNF) and cognitive function are diminished
in people with Parkinson's disease (PD). The relationship of cognitive function and serum …

Lactoferrin is a sialic acid-rich, iron-binding milk glycoprotein, known to have multifunctional
health benefits, including its ability to modulate immune function and facilitate iron …

Axon growth and dendrite development are key processes for the establishment of a
functional neuronal network. Adenosine, which is released by neurons and glia, is a known …