INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …

The chaperome is a large and diverse protein machinery composed of chaperone proteins
and a variety of helpers, such as the co-chaperones, folding enzymes, and scaffolding and …

Cancer cells have the unusual capacity to limit the cost of the mutation load that they harbor
and simultaneously harness its evolutionary potential. This property fuels drug resistance, a …

Transposable elements (TEs) have been recognized as potentially powerful drivers of
genomic evolutionary change, but factors affecting their mobility and regulation remain …

Evolutionary developmental genetics has traditionally been conducted by two groups:
Molecular evolutionists who emphasize divergence between species or higher taxa, and …

Heat shock protein 90 (HSP90) is a molecular chaperone that is required for the function of
various substrate proteins, also known as client proteins. It is proposed that HSP90 buffers …

The process of patterning along the anterior-posterior axis in vertebrates is highly
conserved. The function of Hox genes in the axis patterning process is particularly well …

Hsp90 is a molecular chaperone that aids in the folding of its metastable client proteins. Past
studies have shown that it can exert a strong impact on some cellular pathways by …

Unapređenje ključnih indikatora perofrmansi poslovanja u industriji livarstva radi dostizanja
globalnih standarda procesne i resursne efikasnosti od opšteg je interesa za srpske livnice s …

Natural Selection describes how species have evolved differentially, but it is descriptive, non-
mechanistic. What mechanisms does Nature use to accomplish this feat? One known way in …