Mechanisms of lung injury and bronchopulmonary dysplasia

AH Jobe - American journal of perinatology, 2016 - thieme-connect.com
Although bronchopulmonary dysplasia (BPD) is the most frequent adverse outcome for
infants born at< 30 weeks gestational age, there remain major gaps in understanding the …

Defining the risk and associated morbidity and mortality of severe respiratory syncytial virus infection among infants with chronic lung disease

B Paes, B Fauroux, J Figueras-Aloy, L Bont… - Infectious diseases and …, 2016 - Springer
Abstract Introduction The REGAL (RSV evidence—a geographical archive of the literature)
series provide a comprehensive review of the published evidence in the field of respiratory …

Long-chain polyunsaturated fatty acids and clinical outcomes of preterm infants

A Lapillonne, SJ Moltu - Annals of Nutrition and Metabolism, 2016 - karger.com
Long-chain polyunsaturated fatty acids (LCPUFAs) play specific roles during the perinatal
period and are very important nutrients to consider. The possible effects of LCPUFAs …

Vitamin D and bronchopulmonary dysplasia in preterm infants

KE Joung, HH Burris, LJ Van Marter, TF McElrath… - Journal of …, 2016 - nature.com
Objective: Vitamin D deficiency is associated with asthma and reactive airway disease in
childhood but its potential contribution to bronchopulmonary dysplasia (BPD) in preterm …

Continuous positive airway pressure to prevent neonatal lung injury: how did we get here, and how do we improve?

CJ Wright, RA Polin, H Kirpalani - The Journal of pediatrics, 2016 - jpeds.com
Supporting the respiratory status of the newly born, criti-cally ill premature neonate is a long
held focus of the practicing neonatologist. One could argue that neonatology evolved out of …

Increasing F2-isoprostanes in the first month after birth predicts poor respiratory and neurodevelopmental outcomes in very preterm infants

MA Matthews, JL Aschner, AR Stark, PE Moore… - Journal of …, 2016 - nature.com
Objective: This study examined the association between increased early oxidative stress,
measured by F2-isoprostanes (IsoPs), and respiratory morbidity at term equivalent age and …

Challenges, priorities and novel therapies for hypoxemic respiratory failure and pulmonary hypertension in the neonate

JL Aschner, J Gien, N Ambalavanan, JP Kinsella… - Journal of …, 2016 - nature.com
Future priorities for the management of hypoxemic respiratory failure (HRF) and pulmonary
hypertension include primary prevention of neonatal lung diseases,'precision medicine'and …

Management of hypoxemic respiratory failure and pulmonary hypertension in preterm infants

N Ambalavanan, JL Aschner - Journal of Perinatology, 2016 - nature.com
While diagnoses of hypoxemic respiratory failure (HRF) and pulmonary hypertension (PH) in
preterm infants may be based on criteria similar to those in term infants, management …

The search for treatment of bronchopulmonary dysplasia

A Jobe - JAMA pediatrics, 2016 - jamanetwork.com
make some individuals more vs less susceptible to positive and negative contextual
influences, this will have implications for health services, a point highlighted in the article by …

Mesenchymal stromal cell-based therapies for chronic lung disease of prematurity

L Strueby, B Thebaud - American Journal of Perinatology, 2016 - thieme-connect.com
Advances in perinatal care allow the survival of ever more premature infants. By
approaching the biological limit of viability, survival free of injury becomes more challenging …