[PDF][PDF] SOCS2: physiological and pathological functions

E Letellier, S Haan - Front Biosci (Elite Ed), 2016 - article.imrpress.com
Suppressors of cytokine signalling (SOCS) proteins are modulators of cytokine and growth
factor signalling whose aberrant regulation has been linked to a variety of inflammatory and …

Nanofibrous poly (3-hydroxybutyrate)/poly (3-hydroxyoctanoate) scaffolds provide a functional microenvironment for cartilage repair

KY Ching, OG Andriotis, S Li… - Journal of …, 2016 - journals.sagepub.com
Articular cartilage defects, when repaired ineffectively, often lead to further deterioration of
the tissue, secondary osteoarthritis and, ultimately, joint replacement. Unfortunately, current …

[HTML][HTML] Catabolic and proinflammatory effects of leptin in chondrocytes are regulated by suppressor of cytokine signaling-3

A Koskinen-Kolasa, K Vuolteenaho, R Korhonen… - Arthritis research & …, 2016 - Springer
Background Previous studies provide evidence that adipokine leptin increases production of
catabolic and proinflammatory factors in chondrocytes and serves as a link between obesity …

[HTML][HTML] Demethylation of an NF-κB enhancer element orchestrates iNOS induction in osteoarthritis and is associated with altered chondrocyte cell cycle

MC de Andrés, A Takahashi, ROC Oreffo - Osteoarthritis and Cartilage, 2016 - Elsevier
Objective To examine the methylation profile of the nuclear factor (NF)-κB enhancer region
at− 5.8 kb of inducible nitric oxide synthase (iNOS) and the subsequent role in the induction …

[HTML][HTML] Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

AC Planello, R Singhania, KJ Kron, SD Bailey… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Chronic periodontitis (CP) is a chronic inflammatory disease independently associated with
higher incidence of oral cavity squamous cell carcinoma (OSCC). However, the molecular …

[HTML][HTML] JAK2/STAT3 信号通路介导薯蓣皂苷元对骨性关节炎软骨细胞代谢的影响

LIU Jun, HE Xiaole, Z Ping, Z Shenghu… - Journal of Zhejiang …, 2016 - ncbi.nlm.nih.gov
JAK2/STAT3信号通路介导薯蓣皂苷元对骨性关节炎软骨细胞代谢的影响- PMC Back to Top Skip
to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …

[PDF][PDF] Suppressors of cytokine signalling in ankylosing spondylitis and their associations with disease severity, acute-phase reactants and serum cytokines

CH Chen, HA Chen, HT Liao, CH Liu… - Clin Exp …, 2016 - clinexprheumatol.org
Suppressors of cytokine signalling in ankylosing spondylitis and their associations with disease
severity, acute-phase reactants Page 1 Clinical and Experimental Rheumatology 2016; 34 …

[PDF][PDF] Transcriptional profile of human anti-inflammatory macrophages under homeostatic, activating and pathological conditions

VD Cuevas - 2016 - core.ac.uk
Macrophages are cells of the innate immune system that exhibit a huge phenotypic and
functional heterogeneity, what gives macrophages the ability to sense and respond …

Osteoarthritis and the immune system

MB Goldring, JM Dayer, SR Goldring - Osteoimmunology, 2016 - Elsevier
Osteoarthritis (OA) is the most common joint disorder and is a leading cause of disability in
the adult population. It is now appreciated that all components of the joint, including the …

[PDF][PDF] Bioinformatics analysis of differentially expressed miRNAs in plasma of respiratory distress syndrome

Y Yang, XY Zhou, YS Zou, R Cheng - Int J Clin Exp Med, 2016 - e-century.us
Purpose: This study was aimed to reveal the involvement of miRNAs in RDS by
bioinformatics analysis. Methods: The data in this study came from the paper of Kan et al …