Necrotic cell sensor Clec4e promotes a proatherogenic macrophage phenotype through activation of the unfolded protein response
M Clément, G Basatemur, L Masters, L Baker… - Circulation, 2016 - Am Heart Assoc
Background: Atherosclerotic lesion expansion is characterized by the development of a lipid-
rich necrotic core known to be associated with the occurrence of complications. Abnormal …
rich necrotic core known to be associated with the occurrence of complications. Abnormal …
[HTML][HTML] Endoplasmic reticulum stress in chondrodysplasias caused by mutations in collagen types II and X
K Gawron - Cell Stress and Chaperones, 2016 - Elsevier
The endoplasmic reticulum is primarily recognized as the site of synthesis and folding of
secreted, membrane-bound, and some organelle-targeted proteins. An imbalance between …
secreted, membrane-bound, and some organelle-targeted proteins. An imbalance between …
ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23erl/erl mutant mice
J Hu, B Li, L Apisa, H Yu, S Entenman, M Xu… - Cell death & …, 2016 - nature.com
Hearing loss is one of the most common sensory impairments in humans. Mouse mutant
models helped us to better understand the mechanisms of hearing loss. Recently, we have …
models helped us to better understand the mechanisms of hearing loss. Recently, we have …
C/EBP β mediates endoplasmic reticulum stress regulated inflammatory response and extracellular matrix degradation in LPS-stimulated human periodontal ligament …
Y Bai, Y Wei, L Wu, J Wei, X Wang, Y Bai - International journal of …, 2016 - mdpi.com
Periodontitis is an oral inflammatory disease that not only affects the integrity of local tooth-
supporting tissues but also impacts systemic health. A compositional shift in oral microbiota …
supporting tissues but also impacts systemic health. A compositional shift in oral microbiota …
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway
W Zhang, L Chen, Y Shen, J Xu - Toxicology in Vitro, 2016 - Elsevier
Endoplasmic reticulum (ER) stress-induced cell injury plays an important role in the
development of drug-induced liver injury (DILI). However, little is known about the …
development of drug-induced liver injury (DILI). However, little is known about the …
The protective effect of the earthworm active ingredients on hepatocellular injury induced by endoplasmic reticulum stress
Q Wang, L Duan, Z Xu, J Wang, S Xi - Biomedicine & Pharmacotherapy, 2016 - Elsevier
The earthworm is a widely used Chinese herbal medicine. There are more than 40
prescriptions including earthworms in the “Compendium of Materia Medica”. TCM theory …
prescriptions including earthworms in the “Compendium of Materia Medica”. TCM theory …