Zinc delays the progression of obesity‐related glomerulopathy in mice via down‐regulating P 38 MAPK‐mediated inflammation

M Luo, P Luo, Z Zhang, K Payne, S Watson, H Wu… - …, 2016 - Wiley Online Library
Objective Obesity, particularly child obesity, is one of the most common public health
problems in the world and raises the risk of end‐stage renal disease. Zinc (Zn) is essential …

12-Lipoxygenase inhibition on microalbuminuria in type-1 and type-2 diabetes is associated with changes of glomerular angiotensin II type 1 receptor related to …

HZ Xu, YL Cheng, WN Wang, H Wu, YY Zhang… - International journal of …, 2016 - mdpi.com
(1) Background: 12-lipoxygenase (12-LO) is involved in the development of diabetic
nephropathy (DN). In the present study, we investigated whether 12-LO inhibition may …

Effect of angiotensin II type 1 receptor blocker on 12-lipoxygenase activity and slit diaphragm protein expression in type 2 diabetic rat glomeruli

H Xu, W Wang, Y Zhang, Y Cheng, Z Xu - Journal of Nephrology, 2016 - Springer
Abstract Background The 12-lipoxygenase (12-LO) and angiotensin II (Ang II) interaction
plays an important role in diabetic nephropathy (DN). Proteinuria in DN is associated with …

[引用][C] 血管紧张素Ⅱ1 型受体功能研究进展

孙韬, 臧崇森, 许钟镐 - 中国老年学杂志, 2016