Exposure to bisphenol A (BPA) in Wistar rats reduces sperm quality with disruption of ERK signal pathway

J Li, R Mao, Q Zhou, L Ding, J Tao… - Toxicology …, 2016 - Taylor & Francis
Bisphenol A (BPA) is an estrogenic environmental toxin widely used in the production of
plastics and ubiquitous human exposure to this chemical has been proposed to be a …

Associations of bisphenol A and polychlorinated biphenyls with spermatogenesis and steroidogenesis in two biological fluids from men attending an infertility clinic

J Vitku, J Heracek, L Sosvorova, R Hampl… - Environment …, 2016 - Elsevier
Background In the testis, steroid hormones play an important role in spermatogenesis, the
production of semen, and the maintenance of secondary sex characteristics and libido. They …

Cytotoxic effects of ZnO nanoparticles on mouse testicular cells

Z Han, Q Yan, W Ge, ZG Liu, S Gurunathan… - International journal …, 2016 - Taylor & Francis
Background Nanoscience and nanotechnology are developing rapidly, and the applications
of nanoparticles (NPs) have been found in several fields. At present, NPs are widely used in …

In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction

A Barbonetti, C Castellini, N Di Giammarco… - Reproductive …, 2016 - Elsevier
As bisphenol A (BPA) exerts oxidative/pro-apoptotic effects in several cell types, we
explored whether the in vitro exposure to BPA could affect human sperm integrity through …

[HTML][HTML] Dynamin-related protein 1 inhibition mitigates bisphenol A-mediated alterations in mitochondrial dynamics and neural stem cell proliferation and …

S Agarwal, A Yadav, SK Tiwari, B Seth… - Journal of Biological …, 2016 - ASBMB
The regulatory dynamics of mitochondria comprises well orchestrated distribution and
mitochondrial turnover to maintain the mitochondrial circuitry and homeostasis inside the …

Mitochondrial functionality and chemical compound action on sperm function

S Amaral, RS Tavares, M Baptista… - Current medicinal …, 2016 - ingentaconnect.com
During the last decade, several studies have shown that mitochondrial parameters, such as
integrity, respiratory activity, membrane potential and ROS production are intimately linked …

Protective effect of Cordyceps militaris extract against bisphenol A induced reproductive damage

J Wang, C Chen, Z Jiang, M Wang… - Systems Biology in …, 2016 - Taylor & Francis
This study aimed to investigate the protective effects of Cordyceps militaris (C. militaris)
against reproductive damage induced by bisphenol A (BPA). Rats were administrated 200 …

Effects of 4-nonylphenol on spermatogenesis and induction of testicular apoptosis through oxidative stress-related pathways

P Duan, C Hu, HJ Butler, C Quan, W Chen… - Reproductive …, 2016 - Elsevier
This study tested the hypothesis that prepubertal exposure to 4-nonylphenol (NP) affects
reproductive function in male rats. Twenty-four rats at five-weeks-old were randomly divided …

Differential effects of bisphenol A and estradiol on rat spermatogenesis' establishment

V Brouard, I Guénon, H Bouraima-Lelong… - Reproductive …, 2016 - Elsevier
Several studies have highlighted the negative effects of bisphenol A (BPA), a chemical
compound with estrogenic activity, on reproductive health. To elucidate the impact of BPA on …

The Methylcytosine Dioxygenase Ten-Eleven Translocase-2 (tet2) Enables Elevated GnRH Gene Expression and Maintenance of Male Reproductive Function

JR Kurian, S Louis, KL Keen, A Wolfe… - …, 2016 - academic.oup.com
Reproduction depends on the establishment and maintenance of elevated GnRH
neurosecretion. The elevation of primate GnRH release is accompanied by epigenetic …