Introduction: Brain atrophy measurement in multiple sclerosis (MS) has become an
important outcome for determining patients at risk for developing physical and cognitive …

Our understanding of radiologically isolated syndrome (RIS) is evolving, as new data
emerge on the clinical characterization and the pathophysiological nature of this rare entity …

Aim. To explore the efficacy of home‐based, computerised, cognitive rehabilitation in
patients with multiple sclerosis using neuropsychological assessment and advanced …

Introduction As neurodegeneration is recognized as a major contributor to disability in
multiple sclerosis (MS), brain atrophy quantification could have a high added value in …

Recent studies on patients with clinically isolated syndrome (CIS) and multiple sclerosis
(MS) demonstrated thalamic atrophy. Here we addressed the following question: Is early …

Background Studies disagree on the location of grey matter (GM) atrophy in the multiple
sclerosis (MS) brain. Aim To examine the consistency between FSL, FreeSurfer, SPM for GM …

Purpose To investigate the patterns of regional gray matter (GM) and white matter (WM)
atrophy, WM microstructural tissue damage, and changes in patients with a clinically …

Background and purpose Vitamin D status has been associated with inflammatory activity in
multiple sclerosis (MS), but it is not known if it is associated with gray matter volume, the loss …

Background: Posterior fossa lesions are common in pediatric-onset multiple sclerosis (MS),
which is of concern, given the known role of the cerebellum in cognition. Objectives: To …

Background Multiple sclerosis can impair cognition from the early stages and has been
shown to be associated with gray matter damage in addition to white matter pathology …