[PDF][PDF] An overview of heterologous expression host systems for the production of recombinant proteins

AR Gomes, SM Byregowda, BM Veeregowda… - Adv. Anim. Vet …, 2016 - academia.edu
With the advent of recombinant DNA technology, cloning and expression of numerous
mammalian genes in different systems have been explored to produce many therapeutics …

The transgenic animal platform for biopharmaceutical production

LR Bertolini, H Meade, CR Lazzarotto, LT Martins… - Transgenic …, 2016 - Springer
The recombinant production of therapeutic proteins for human diseases is currently the
largest source of innovation in the pharmaceutical industry. The market growth has been the …

Cellular reprogramming in farm animals: an overview of iPSC generation in the mammalian farm animal species

J Ogorevc, S Orehek, P Dovč - Journal of Animal Science and …, 2016 - Springer
Establishment of embryonic stem cell (ESC) lines has been successful in mouse and
human, but not in farm animals. Development of direct reprogramming technology offers an …

Nanoparticles as a tool for transfection and transgenesis–a review

N Dzięgiel - Annals of Animal Science, 2016 - sciendo.com
Nanoparticles can be an alternative for currently used viral and non-viral systems of
transporting exogenous DNA into cells, and furthermore, can be an effective way to produce …

Embryonic stem‐like cells from rabbit blastocysts cultured with melatonin could differentiate into three germ layers in vitro and in vivo

R Wei, X Zhao, H Hao, W Du… - Molecular Reproduction …, 2016 - Wiley Online Library
The rabbit is considered an important model animal from which to obtain embryonic stem
cells because of the utility of this animal in physiology and reproductive research. Here, we …

Oral administration of silkworm-produced gad65 and insulin bi-autoantigens against type 1 diabetes

B Liu, Y Yue, Y Yang, Y Jin - Plos one, 2016 - journals.plos.org
Induction of mucosal tolerance by oral administration of protein antigens is a potential
therapeutic strategy for preventing and treating type 1 diabetes (T1D); however, the …

Transgenic farm animals: the status of research and prospects

NA Zinovieva, NA Volkova, VA Bagirov… - Russian Journal of …, 2016 - Springer
The production of transgenic animals is of great interest for current basic and applied
research. This article is a review of methods for the production of transgenic farm animals …

Improved development of somatic cell cloned bovine embryos by a mammary gland epithelia cells in vitro model

X He, L Ma, X He, W Si… - Journal of Veterinary …, 2016 - synapse.koreamed.org
Previous studies have established a bovine mammary gland epithelia cells in vitro model by
the adenovirus-mediated telomerase (hTERT-bMGEs). The present study was conducted to …

Preclinical evaluation of a diabody-based 177Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy in a non-Hodgkin lymphoma mouse model

T Weber, B Bötticher, MAE Arndt, W Mier, M Sauter… - Cancer Letters, 2016 - Elsevier
Radioimmunotherapy is considered as treatment option in recurrent and/or refractory B-cell
non-Hodgkin lymphoma (B-NHL). To overcome the dose limiting bone marrow toxicity of IgG …

Рекомбинантный гонадотропин для индукции суперовуляции у крупного рогатого скота: состояние и перспективы (обзор)

СА Бурсаков, СН Ковальчук, ДВ Попов… - Проблемы биологии …, 2016 - cyberleninka.ru
Важным звеном технологии трансплантации эмбрионов крупного рогатого скота
является гормональная стимуляция суперовуляции у коров-доноров, которая …