Secondary lymphoid tissues share the important function of bringing together antigens and
rare antigen‐specific lymphocytes to foster induction of adaptive immune responses. Peyer's …

Leukocyte trafficking to the small and large intestines is tightly controlled to maintain
intestinal immune homeostasis, mediate immune responses, and regulate inflammation. A …

INTRODUCTION Secretory immunoglobulin A (IgA) is made by intestinal plasma cells and
has roles both in protection from gut pathogens and in maintaining homeostasis of intestinal …

Notch has a well-defined role in controlling cell fate decisions in the embryo and the adult
epidermis and immune systems, yet emerging evidence suggests Notch also directs non …

Chemokines belong to a superfamily of small, cytokine-like proteins, which induce multiple
physiological functions, particularly cytoskeletal rearrangement and compartment-specific …

Lupus nephritis (LN) is a major cause of morbidity and mortality in the patients with systemic
lupus erythematosus (SLE), an autoimmune disease with damage to multiple organs …

The gut CD4+ T cells, particularly the T helper type 17 (Th17) subset, are not completely
restored in most HIV-1-infected individuals despite combined antiretroviral therapy, when …

ABSTRACT CCL20 is a member of the macrophage inflammatory protein family and is
reported to signal monogamously through the receptor CCR6. Although studies have …

Aim To evaluate whether the effect of dendritic cells (DCs) on chronic obstructive pulmonary
disease (COPD) can be relieved by blocking CCL20. Methods 30 Wistar rats were randomly …

Chemokines and their receptors play an important role in cell trafficking and recruitment. The
CCR6 chemokine receptor, selectively expressed on leukocyte populations, has been …