The recent increase in our knowledge of human gut microbiota has changed our view on
antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially …

The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and
North America, the term is generally applied according to the European Association for the …

The gut microbiota has recently evolved as a new important player in the pathophysiology of
many intestinal and extraintestinal diseases. The liver is the organ which is in closest contact …

Objective Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease often
leading to end-stage liver disease. Its pathogenesis remains largely unknown, although …

Increasing evidence suggests a role of intestinal dysbiosis in obesity and non-alcoholic fatty
liver disease (NAFLD). But it remains unknown in nonobese NAFLD. This prospective, cross …

Several studies have described a dose-dependent effect of alcohol on human health with
light to moderate drinkers having a lower risk of all-cause mortality than abstainers, while …

Cirrhosis is associated with brain dysfunction known as hepatic encephalopathy (HE). The
mechanisms behind HE are unclear although hyperammonemia and systemic inflammation …

We selected 42 early‐stage primary biliary cirrhosis (PBC) patients and 30 healthy controls
(HC). Metagenomic sequencing of the 16S rRNA gene was used to characterize the fecal …

The available evidence suggests that alterations in gut microbiota may be tightly linked to
the increase in microbial translocation and systemic inflammation in patients with human …

Background & Aims In advanced cirrhosis, gut bacterial translocation is the consequence of
intestinal barrier disruption and leads to bacterial infection. Bile acid abnormalities in …