The epidemiology of Parkinson's disease: risk factors and prevention
A Ascherio, MA Schwarzschild - The Lancet Neurology, 2016 - thelancet.com
Since 2006, several longitudinal studies have assessed environmental or behavioural
factors that seem to modify the risk of developing Parkinson's disease. Increased risk of …
factors that seem to modify the risk of developing Parkinson's disease. Increased risk of …
Role of uric acid metabolism‐related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and nonalcoholic steatohepatitis
A Kushiyama, Y Nakatsu, Y Matsunaga… - Mediators of …, 2016 - Wiley Online Library
Uric acid (UA) is the end product of purine metabolism and can reportedly act as an
antioxidant. However, recently, numerous clinical and basic research approaches have …
antioxidant. However, recently, numerous clinical and basic research approaches have …
Influence of cigarette smoking on ALS outcome: a population-based study
A Calvo, A Canosa, D Bertuzzo, P Cugnasco… - Journal of Neurology …, 2016 - jnnp.bmj.com
Objective To assess the prognostic influence of premorbid smoking habits and vascular risk
profile on amyotrophic lateral sclerosis (ALS) phenotype and outcome in a population-based …
profile on amyotrophic lateral sclerosis (ALS) phenotype and outcome in a population-based …
[HTML][HTML] Antecedent disease and amyotrophic lateral sclerosis: what is protecting whom?
SK Hollinger, IS Okosun, CS Mitchell - Frontiers in neurology, 2016 - frontiersin.org
Multiple studies have shown that antecedent diseases are less prevalent in amyotrophic
lateral sclerosis (ALS) patients than the general age-matched population, which suggests …
lateral sclerosis (ALS) patients than the general age-matched population, which suggests …
The influence of serum uric acid on bone mineral density, hip geometry, and fracture risk: the Rotterdam Study
T Muka, EAL de Jonge… - The Journal of …, 2016 - academic.oup.com
Context: The role of uric acid (UA) in skeletal metabolism remains to be unraveled.
Objective: We prospectively investigated the association between UA, bone mineral density …
Objective: We prospectively investigated the association between UA, bone mineral density …
Administration of uric acid in the emergency treatment of acute ischemic stroke
L Llull, S Amaro, Á Chamorro - Current neurology and neuroscience …, 2016 - Springer
Oxidative stress is one of the main mechanisms implicated in the pathophysiology of
inflammatory and neurodegenerative diseases of the central nervous system (CNS). Uric …
inflammatory and neurodegenerative diseases of the central nervous system (CNS). Uric …
Further development of biomarkers in amyotrophic lateral sclerosis
H Blasco, P Vourc'h, PF Pradat… - Expert Review of …, 2016 - Taylor & Francis
Introduction: Amyotrophic lateral sclerosis (ALS) is an idiopathic neurodegenerative disease
usually fatal in less than three years. Even if standard guidelines are available to diagnose …
usually fatal in less than three years. Even if standard guidelines are available to diagnose …
血清尿酸水平与肌萎缩侧索硬化症的关系
段玉香， 樊东升 - 中华医学杂志, 2016 - cqvip.com
目的探讨血清尿酸(UA) 水平与肌萎缩侧索硬化症(ALS) 的关系. 方法检测2010 年1 月至2014
年12 月北京大学第三医院门诊和住院164 例ALS 患者和164 名性别, 年龄匹配的健康体检者的 …
年12 月北京大学第三医院门诊和住院164 例ALS 患者和164 名性别, 年龄匹配的健康体检者的 …
中药对肌萎缩侧索硬化症的研究进展(下)
邓文龙 - 中药药理与临床, 2016 - cqvip.com
1.10. 6 七叶亭(esculetin) 除了抗菌作用而外, 其主要作用还包括抗肿瘤作用, 神经保护作用,
血管保护作用, 抗氧化作用以及抗炎, 镇痛, 保肝等作用[140], 此外, 还可能是II …
血管保护作用, 抗氧化作用以及抗炎, 镇痛, 保肝等作用[140], 此外, 还可能是II …
尿酸对急性缺血性卒中神经保护作用的研究进展
张健芳， 蒋亚斌 - 广东医学, 2016 - cqvip.com
尿酸(uric acid, UA) 是嘌呤代谢的终产物, 也是人类血液含量最丰富的天然水溶性抗氧化剂.
以往的研究一直把UA 升高作为心脑血管疾病的危险因素, 近些年来研究发现UA …
以往的研究一直把UA 升高作为心脑血管疾病的危险因素, 近些年来研究发现UA …