Engineered BDNF producing cells as a potential treatment for neurologic disease
P Deng, JD Anderson, AS Yu, G Annett… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Brain-derived neurotrophic factor (BDNF) has been implicated in wide range of
neurological diseases and injury. This neurotrophic factor is vital for neuronal health …
neurological diseases and injury. This neurotrophic factor is vital for neuronal health …
Neuroprotective therapies for multiple sclerosis and other demyelinating diseases
P Villoslada - Multiple Sclerosis and Demyelinating Disorders, 2016 - Springer
Abstract Damage to the Central Nervous Systems (CNS) in Multiple Sclerosis (MS) seems to
be mainly due to chronic inflammation of the CNS with superimposed bouts of inflammatory …
be mainly due to chronic inflammation of the CNS with superimposed bouts of inflammatory …
Stabilising cubosomes with Tween 80 as a step towards targeting lipid nanocarriers to the blood–brain barrier
Coating nanoparticles with the surfactant Tween 80 have been previously shown to
enhance drug delivery across the blood–brain barrier (BBB). The aim of this study was to …
enhance drug delivery across the blood–brain barrier (BBB). The aim of this study was to …
Focused ultrasound-enhanced intranasal brain delivery of brain-derived neurotrophic factor
H Chen, GZX Yang, H Getachew, C Acosta… - Scientific reports, 2016 - nature.com
The objective of this study was to unveil the potential mechanism of focused ultrasound
(FUS)-enhanced intranasal (IN) brain drug delivery and assess its feasibility in the delivery …
(FUS)-enhanced intranasal (IN) brain drug delivery and assess its feasibility in the delivery …
Functional recovery after cervical spinal cord injury: role of neurotrophin and glutamatergic signaling in phrenic motoneurons
Cervical spinal cord injury (SCI) interrupts descending neural drive to phrenic motoneurons
causing diaphragm muscle (DIAm) paralysis. Recent studies using a well-established model …
causing diaphragm muscle (DIAm) paralysis. Recent studies using a well-established model …
Stem cells therapy for ALS
L Mazzini, A Vescovi, R Cantello, M Gelati… - Expert Opinion on …, 2016 - Taylor & Francis
Introduction: Despite knowledge on the molecular basis of amyotrophic lateral sclerosis
(ALS) having quickly progressed over the last few years, such discoveries have not yet …
(ALS) having quickly progressed over the last few years, such discoveries have not yet …
Unchanged neurotrophic factors and their receptors correlate with sparing in extraocular muscles in amyotrophic lateral sclerosis
VM Harandi, ARN Gaied, T Brännström… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: To investigate the impact of amyotrophic lateral sclerosis (ALS) on the extraocular
muscles (EOMs) by examining the distribution of neurotrophic factors (NTFs) and their …
muscles (EOMs) by examining the distribution of neurotrophic factors (NTFs) and their …
Trophic factors in the therapeutic challenge against ALS: Current research directions
A Sobuś, B Machaliński - Update on Amyotrophic Lateral …, 2016 - books.google.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder, which up to date
remains incurable. Multiple experimental approaches toward finding an effective way of …
remains incurable. Multiple experimental approaches toward finding an effective way of …
A muscle perspective on the pathophysiology of amyotrophic lateral sclerosis: Differences between extraocular and limb muscles
VM Harandi - 2016 - diva-portal.org
Background: Amyotrophic lateral sclerosis (ALS) is a late-onset progressive
neurodegenerative disorder. ALS has been traditionally believed to be primarily a motor …
neurodegenerative disorder. ALS has been traditionally believed to be primarily a motor …