Prevention of muscle wasting and osteoporosis: the value of examining novel animal models
BD Reilly, CE Franklin - Journal of experimental biology, 2016 - journals.biologists.com
Bone mass and skeletal muscle mass are controlled by factors such as genetics, diet and
nutrition, growth factors and mechanical stimuli. Whereas increased mechanical loading of …
nutrition, growth factors and mechanical stimuli. Whereas increased mechanical loading of …
Cardiac‐secreted factors as peripheral metabolic regulators and potential disease biomarkers
CM Dewey, KM Spitler, JM Ponce, DD Hall… - Journal of the …, 2016 - Am Heart Assoc
In the United States alone, 1 person dies from a coronary event approximately every 1.5
minutes. 1 Cardiovascular disease (CVD) encompasses larger subclasses of diseases, such …
minutes. 1 Cardiovascular disease (CVD) encompasses larger subclasses of diseases, such …
[HTML][HTML] Establishment and phenotypic analysis of an Mstn knockout rat
H Gu, Y Cao, B Qiu, Z Zhou, R Deng, Z Chen… - Biochemical and …, 2016 - Elsevier
Myostatin (Mstn) is an inhibitor of myogenesis, regulating the number and size of skeletal
myocytes. In addition to its myogenic regulatory function, Mstn plays important roles in the …
myocytes. In addition to its myogenic regulatory function, Mstn plays important roles in the …
System-L amino acid transporters play a key role in pancreatic β-cell signalling and function
Q Cheng, VD Beltran, SMH Chan… - Journal of …, 2016 - jme.bioscientifica.com
The differential, tissue-specific regulation of oxytocin (OT) binding sites allows the
neurohypophysial nonapeptide OT to fulfill a dual role: to induce uterine contractions at …
neurohypophysial nonapeptide OT to fulfill a dual role: to induce uterine contractions at …
Gene Expression and Polymorphism of Myostatin Gene and its Association with Growth Traits in Chicken
K Dushyanth, TK Bhattacharya, R Shukla… - Animal …, 2016 - Taylor & Francis
Myostatin is a member of TGF-β super family and is directly involved in regulation of body
growth through limiting muscular growth. A study was carried out in three chicken lines to …
growth through limiting muscular growth. A study was carried out in three chicken lines to …
Myostatin attenuation in vivo reduces adiposity, but activates adipogenesis
A potentially novel approach for treating obesity includes attenuating myostatin as this
increases muscle mass and decreases fat mass. Notwithstanding, conflicting studies report …
increases muscle mass and decreases fat mass. Notwithstanding, conflicting studies report …
WFIKKN1 and WFIKKN2:“Companion” proteins regulating TGFB activity
O Monestier, V Blanquet - Cytokine & growth factor reviews, 2016 - Elsevier
Abstract The WFIKKN (WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin domain-
containing) protein family is composed of two multidomain proteins: WFIKKN1 and …
containing) protein family is composed of two multidomain proteins: WFIKKN1 and …
Identification of Deleterious Mutations in Myostatin Gene of Rohu Carp (Labeo rohita) Using Modeling and Molecular Dynamic Simulation Approaches
KD Rasal, V Chakrapani, SK Patra… - BioMed research …, 2016 - Wiley Online Library
The myostatin (MSTN) is a known negative growth regulator of skeletal muscle. The mutated
myostatin showed a double‐muscular phenotype having a positive significance for the …
myostatin showed a double‐muscular phenotype having a positive significance for the …
Muscle hypertrophy in transgenic mice due to over-expression of porcine myostatin mutated at its cleavage site
LL Qian, P GAO, S JIANG, Q WANG, C CAI… - Journal of Integrative …, 2016 - Elsevier
Myostatin, a member of the transforming growth factor beta (TGF-β) superfamily, is a
dominant inhibitor that acts to limit skeletal muscle growth and development. In this study …
dominant inhibitor that acts to limit skeletal muscle growth and development. In this study …