BACKGROUND To obtain better insight into the biology of acute myeloid leukemia (AML) in
various age groups, this study focused on the genetic changes occurring during a lifetime …

Genetic abnormalities and early treatment response are the main prognostic factors in acute
myeloid leukemia (AML). Acute megakaryoblastic leukemia (AMKL) is a rare subtype of …

Background: Cytogenetics is one of the most important diagnostic parameters in the
classification of acute leukemia. Recurrent chromosomal aberrations in acute leukemia have …

Background Studies on adolescents and young adults with acute lymphoblastic leukemia
suggest better results when using pediatric protocols for adult patients, while corresponding …

A better understanding of factors associated with early death and survival among children,
adolescents and young adults with acute myeloid leukaemia (AML) may guide health policy …

Geographic variation and ethnicity have been implicated to influence the outcome of
pediatric acute myeloid leukemia (AML). Furthermore, survival outcomes from developing …

Trisomy 8 (+ 8) is a common cytogenetic aberration in acute myeloid leukemia (AML);
however, the impact of+ 8 in pediatric AML is largely unknown. We retrospectively …

1 Vachon CM, Kyle RA, Therneau TM, Foreman BJ, Larson DR, Colby CL et al. Increased
risk of monoclonal gammopathy in first-degree relatives of patients with multiple myeloma or …

Introducción: las neoplasias hematológicas tienen origen clonal y se caracterizan por
presentar gran heterogeneidad genética. El desarrollo de la citogenética molecular a través …

Background Nucleophosmin gene (NPM1) mutation may be a good molecular marker for
assessing the clinical status and predicting the outcomes in AML patients. We evaluated the …