The International Collaboration in Asthma, Allergy and Immunology initiated an international
coalition among the American Academy of Allergy, Asthma & Immunology; the European …

Primary antibody deficiencies (PADs) are the most common form of primary
immunodeficiency and predispose to severe and recurrent pulmonary infections, which can …

Genetic defects of the immune system are referred to as primary immunodeficiencies (PIDs).
These immunodeficiencies are clinically and immunologically heterogeneous and …

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare
primary immunodeficiency disorder typically caused by homozygous AIRE mutations. It …

OBJECTIVES: The objective of this study was to study the prevalence of gastrointestinal (GI)
symptoms and histopathology in patients with common variable immunodeficiency (CVID) …

Common variable immunodeficiency (CVID) is the most common symptomatic primary
immunodeficiency characterized by low immunoglobulin (Ig) G and IgA, and/or IgM. In …

Granulomas are clusters of immune cells. These structures can be formed in reaction to
infection and display signs of necrosis, such as in tuberculosis. Alternatively, in several …

Background Kabuki syndrome (KS) is a complex multisystem developmental disorder
associated with mutation of genes encoding histone-modifying proteins. In addition to …

Natural Killer (NK) cells have been shown to exert antiviral and antitumoural activities.
Nevertheless most available data are derived from mouse models and functions of these …

Common variable immunodeficiency (CVID) is frequently complicated by the development of
autoimmune and lymphoproliferative diseases. With widespread use of immunoglobulin …