Indoles—A promising scaffold for drug development

TV Sravanthi, SL Manju - European Journal of Pharmaceutical Sciences, 2016 - Elsevier
Generally, heterocycles occupy a prominent place in chemistry due to their wide range of
applications in the fields of drug design, photochemistry, agrochemicals, dyes and so on …

A comprehensive review of N-heterocycles as cytotoxic agents

D Kumar, S Kumar Jain - Current Medicinal Chemistry, 2016 - ingentaconnect.com
Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …

[HTML][HTML] One-pot synthesis and in-vitro anticancer evaluation of 5-(2′-indolyl) thiazoles

BR Vaddula, MP Tantak, R Sadana, MA Gonzalez… - Scientific Reports, 2016 - nature.com
Abstract A series of 5-(2′-indolyl) thiazoles were synthesized and evaluated for their
cytotoxicity against selected human cancer cell lines. The reaction of thioamides 3 with 3 …

Oxazole: A Promising Building Block for the Development of Potent Antitumor Agents.

H Zhou, JQ Cheng, ZS Wang, FH Chen… - Current Topics in …, 2016 - europepmc.org
Oxazole derivatives are found to have a variety of biological activities. A large number of
studies have revealed their outstanding anticancer activities. Here we review four different …

A one-pot tandem approach for the synthesis of 5-(het) aryloxazoles from substituted (het) aryl methyl alcohols and benzyl bromides

KSV Kumar, TR Swaroop, N Rajeev, AC Vinayaka… - Synlett, 2016 - thieme-connect.com
A new modified van Leusen strategy has been developed for the synthesis of biologically
significant 5-substituted oxazoles by the reaction of (het) aryl methyl alcohols or benzyl …

A series of 2, 4, 5-trisubstituted oxazole: Synthesis, characterization and DFT modelling

VS Kadam, SG Shaikh, AL Patel - Journal of Molecular Structure, 2016 - Elsevier
Abstract A new series of 2, 4, 5-trisubstituted oxazole were synthesized with good yields
using simple methodology. All the compounds were thoroughly characterized by IR, NMR (1 …

[PDF][PDF] Chemistry & Biology Interface

N Mor, N Raghav - Chemistry & Biology, 2016 - researchgate.net
Curcumin, an important constituent of turmeric used in the traditional medicinal system has
suffered considerable controversy. Classification as pan-assay interference compounds and …

[PDF][PDF] One-pot synthesis and in-vitro anticancer evaluation of 5-(2′-indolyl) thiazoles

D Kumar - 2016 - academia.edu
A series of 5-(2′-indolyl) thiazoles were synthesized and evaluated for their cytotoxicity
against selected human cancer cell lines. The reaction of thioamides 3 with 3 …