Regarding the 13 known mammalian aquaporins (AQPs), their functions in their expressing
tissues, effects of their mutation/polymorphisms in humans, and effects of knockout of their …

Major intrinsic protein (MIP) is a functional water-channel (AQP0) that also plays a key role
in establishing lens fiber cell architecture. Genetic variants of MIP have been associated with …

In this work we have analyzed the expression levels of the main aquaporins (AQPs)
expressed in human lens epithelial cells (HLECs) using 112 samples from patients treated …

Major intrinsic protein or aquaporin-0 (MIP/AQP0) functions as a water channel and a cell-
junction molecule in the vertebrate eye lens. Loss of MIP function in the lens leads to …

AQP0 water channels are the most abundant proteins expressed in the mammalian lens
fiber membranes where they are essential for lens development and transparency. Unlike …

ABSTRACT P determination of aquaporins has led to a deep understanding of water and
solute permeation by these small integral membrane proteins. Atomic structures have …

Transportation of water is essential for the maintenance of lens homeostasis, and members
of the aquaporin (AQP) family have been found to mediate the water permeability of lens …

UNIVERSIDAD COMPLUTENSE DE MADRID Page 1 UNIVERSIDAD COMPLUTENSE DE
MADRID FACULTAD DE ÓPTICA Y OPTOMETRÍA Departamento de Bioquímica y Biología …