Tumor hypoxia: a new PET imaging biomarker in clinical oncology

N Tamaki, K Hirata - International journal of clinical oncology, 2016 - Springer
Tumor hypoxia is associated with tumor progression and resistance to various treatments.
Noninvasive imaging using positron emission tomography (PET) and F-18-labeled …

Metabolic imaging to assess treatment response to cytotoxic and cytostatic agents

NJ Serkova, SG Eckhardt - Frontiers in oncology, 2016 - frontiersin.org
For several decades, cytotoxic chemotherapeutic agents were considered the basis of
anticancer treatment for patients with metastatic tumors. A decrease in tumor burden …

Decision trees predicting tumor shrinkage for head and neck cancer: implications for adaptive radiotherapy

M Surucu, KK Shah, I Mescioglu… - … in cancer research …, 2016 - journals.sagepub.com
Objective: To develop decision trees predicting for tumor volume reduction in patients with
head and neck (H&N) cancer using pretreatment clinical and pathological parameters …

Hypoxia as a biomarker and for personalized radiation oncology

D Vordermark, MR Horsman - Molecular Radio-Oncology, 2016 - Springer
Tumor hypoxia is a clinically relevant cause of radiation resistance. Direct measurements of
tumor oxygenation have been performed predominantly with the Eppendorf histograph and …

The reoxygenation of hypoxia and the reduction of glucose metabolism in head and neck cancer by fractionated radiotherapy with intensity-modulated radiation …

S Okamoto, T Shiga, K Yasuda, S Watanabe… - European journal of …, 2016 - Springer
Purpose The purpose of this study was to prospectively investigate reoxygenation in the
early phase of fractionated radiotherapy and serial changes of tumoricidal effects associated …

[HTML][HTML] Newer positron emission tomography radiopharmaceuticals for radiotherapy planning: an overview

P Sharma, A Mukherjee - Annals of translational medicine, 2016 - ncbi.nlm.nih.gov
Positron emission tomography-computed tomography (PET-CT) has changed cancer
imaging in the last decade, for better. It can be employed for radiation treatment planning of …

Analysis of pairwise correlations in multi-parametric PET/MR data for biological tumor characterization and treatment individualization strategies

S Leibfarth, U Simoncic, D Mönnich, S Welz… - European journal of …, 2016 - Springer
Purpose The aim of this pilot study was to explore simultaneous functional PET/MR for
biological characterization of tumors and potential future treatment adaptations. To …

Assessment of treatment response with diffusion-weighted MRI and dynamic contrast-enhanced MRI in patients with early-stage breast cancer treated with single …

C Wang, JK Horton, FF Yin… - Technology in cancer …, 2016 - journals.sagepub.com
Single-dose preoperative stereotactic body radiotherapy is a novel radiotherapy technique
for the early-stage breast cancer, and the treatment response pattern of this technique needs …

PET-based quantification of statistical properties of hypoxic tumor subvolumes in head and neck cancer

R Chirla, LG Marcu - Physica Medica, 2016 - Elsevier
Purpose PET hypoxia imaging of head and neck cancer (HNC) has the potential to stratify
the response to radiochemotherapy. The aim of this work was to quantify the statistical …

FMISO as a biomarker for clinical radiation oncology

S Zschaeck, J Steinbach, EGC Troost - Molecular Radio-Oncology, 2016 - Springer
Tumour hypoxia is a well-known negative prognostic marker in almost all solid tumours.[18F]
Fluoromisonidazole (FMISO)-positron emission tomography (PET) is a non-invasive method …