Intestinal epithelial cells apically express glycans, especially α1, 2-fucosyl linkages, which
work as a biological interface for the host–microbe interaction. Emerging studies have …

The inflammatory diseases that are most strongly associated with major histocompatibility
Complex class I (MHC-I) alleles are also influenced by endoplasmic reticulum …

The human major histocompatibility complex (MHC) region has been shown to be
associated with numerous diseases. However, it remains a challenge to pinpoint the causal …

Targeted sequencing of sixteen SLE risk loci among 1349 Caucasian cases and controls
produced a comprehensive dataset of the variations causing susceptibility to systemic lupus …

Polypoidal choroidal vasculopathy (PCV), a subtype of'wet'age-related macular
degeneration (AMD), constitutes up to 55% of cases of wet AMD in Asian patients. In …

Although genome-wide association studies have revealed important insights into the global
genetic basis of psoriasis, the findings require further investigation. At present, the known …

Представлены современные сведения об иммунных механизмах развития псориаза.
Воспаление в коже больных псориазом рассматривается как аутоиммунный процесс, в …

More than a million childhood diarrhoeal episodes occur worldwide each year, and in
developed countries a considerable part of them are caused by viral infections. In this study …

Background Psoriasis is a chronic inflammatory skin disease characterized by epidermal
hyperproliferation and altered keratinocyte differentiation and inflammation and is caused by …

The protease activity of the paracaspase mucosa-associated lymphoid tissue lymphoma
translocation gene 1 (MALT1) plays an important role in antigen receptor-mediated …