Cancer is a prominent cause of death in global. Currently, the numbers of drugs that are in
clinical practice are having a high prevalence of side effect and multidrug resistance …

Overactivation of PI3K/Akt/mTOR is linked with carcinogenesis and serves a potential
molecular therapeutic target in treatment of various cancers. Herein, we report the synthesis …

Persistent activation of signal transducer and activator of transcription 3 (STAT3) is
associated with the progression of a range of tumors. In this report, we present the …

Aberrant activation of nuclear factor kappa B (NF-κB) has been linked with the pathogenesis
of several proinflammatory diseases including number of cancers and inflammatory bowel …

Bcl homologs prominently contribute to apoptotic resistance in cancer cells and serve as
molecular targets in treatment of various cancers. Herein, we report the synthesis of biphenyl …

Triptolide Inhibits Invasion and Tumorigenesis of Hepatocellular Carcinoma MHCC-97H Cells
Through NF-κB Signaling - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Cancer metastasis is the major cause of cancer-related death. Chemoprevention is defined
as the use of natural or synthetic substances to prevent cancer formation or cancer progress …

The efficacy of thiazolidin-4-ones as synthons for diverse biological small molecules has
given impetus to anti-bacterial studies. Our work aims to synthesize novel bioactive …

Neste momento só tenho gratidão. À Deus que sempre me deu forças para superar todos os
obstáculos da minha vida e mesmo quando não achei que conseguiria Ele estava lá me …

As a part of our ongoing studies in developing new coumarin derivatives we describe the
synthesis of novel 7-carbethoxyamino-4-(R) arylaminomethyl coumarins. The synthesized …