The anatomical architecture of the human liver and the diversity of its immune components
endow the liver with its physiological function of immune competence. Adaptive immunity is …

Highlights•Viral capsid proteins interact with nucleic acids and proteins to modulate cellular
responses.•HCV Core interacts with cellular proteins to change lipid synthesis, proliferation …

Hepatitis B virus (HBV) and hepatitis C virus (HCV) are among the most endemic pathogens
worldwide, with more than 500 million people globally currently infected with these viruses …

In order to investigate the mechanisms of persistent foot-and-mouth disease virus (FMDV)
infection in cattle, transcriptome alterations associated with the FMDV carrier state were …

AIM: To investigate killer inhibitory and activating receptor expression by natural killer (NK),
natural killer T-like (NKT-like) and CD8+ T lymphocytes in patients with chronic hepatitis C …

Objectives To assess if peripheral T cell populations in children with chronic hepatitis C virus
(HCV) infection would show evidence of activation/exhaustion and an attenuated functional …

The immunological result of infection with Hepatitis C virus (HCV) depends on the delicate
balance between a vigorous immune response that may clear the infection, but with a risk of …

Despite its importance in shaping adaptive immune responses, viral clearance, and immune-
based inflammation, tissue-specific innate immunity remains poorly characterized for …

Generalized CD8+ T-cell impairment in chronic hepatitis C virus (HCV) infection and the
contribution of liver-infiltrating CD8+ T-cells to the immunopathogenesis of this infection …

Human hepatitis B virus (HBV) core antigen (HBcAg) can act as an adjuvant in hepatitis C
virus (HCV)-based DNA vaccines. Since two billion people are, or have been, in contact with …