Until recently, it was thought that the role of the mitochondrial genome was confined to
encoding key proteins that generate ATP through the process of oxidative phosphorylation …

Mitochondrial DNA replication is critical for maintaining mtDNA copy number to generate
sufficient cellular energy that is required for development and for functional cells. In early …

An increasing number of women fail to achieve pregnancy due to either failed fertilization or
embryo arrest during preimplantation development. This often results from decreased oocyte …

The field of mitochondrial epigenetics has received increased attention in recent years and
changes in mitochondrial DNA (mtDNA) methylation has been implicated in a number of …

Although mitochondrial DNA has been implicated in diseases such as cancer, its role
remains to be defined. Using three models of tumorigenesis, namely glioblastoma …

For a long time, it was perceived that the mitochondrial genome (mtDNA) was primarily
associated with energy production, as it encodes key genes associated with the electron …

Replication of mitochondrial DNA (mtDNA) is important for ensuring that cells have sufficient
mtDNA copy number to meet their specific requirements for the generation of cellular energy …

L'atrophie optique autosomique dominante (ADOA) est une maladie mitochondriale rare.
Les cellules ganglionnaires de la rétine (CGRs) et les axones qui forment le nerf optique …