Dopamine reward prediction-error signalling: a two-component response

W Schultz - Nature reviews neuroscience, 2016 - nature.com
Environmental stimuli and objects, including rewards, are often processed sequentially in
the brain. Recent work suggests that the phasic dopamine reward prediction-error response …

[HTML][HTML] Striatal circuits as a common node for autism pathophysiology

MV Fuccillo - Frontiers in neuroscience, 2016 - frontiersin.org
Autism spectrum disorders (ASD) are characterized by two seemingly unrelated symptom
domains—deficits in social interactions and restrictive, repetitive patterns of behavioral …

Reward functions of the basal ganglia

W Schultz - Journal of neural transmission, 2016 - Springer
Besides their fundamental movement function evidenced by Parkinsonian deficits, the basal
ganglia are involved in processing closely linked non-motor, cognitive and reward …

Gut permeability and microbiota in Parkinson's disease: role of depression, tryptophan catabolites, oxidative and nitrosative stress and melatonergic pathways

G Anderson, M Seo, M Berk… - Current …, 2016 - ingentaconnect.com
Background: Increased gut permeability (leaky gut) and alterations in gut microbiota are now
widely accepted as relevant to the etiology, course and treatment of many neuropsychiatric …

A dynamic code for economic object valuation in prefrontal cortex neurons

KI Tsutsui, F Grabenhorst, S Kobayashi… - Nature …, 2016 - nature.com
Neuronal reward valuations provide the physiological basis for economic behaviour. Yet,
how such valuations are converted to economic decisions remains unclear. Here we show …

A quantitative analysis of context-dependent remapping of medial frontal cortex neurons and ensembles

L Ma, JM Hyman, D Durstewitz, AG Phillips… - Journal of …, 2016 - Soc Neuroscience
The frontal cortex has been implicated in a number of cognitive and motivational processes,
but understanding how individual neurons contribute to these processes is particularly …

Prefrontal cortical inactivations decrease willingness to expend cognitive effort on a rodent cost/benefit decision-making task

JG Hosking, PJ Cocker, CA Winstanley - Cerebral Cortex, 2016 - academic.oup.com
Personal success often necessitates expending greater effort for greater reward but, equally
important, also requires judicious use of our limited cognitive resources (eg, attention) …

[HTML][HTML] Aberrant neural signatures of decision-making: Pathological gamblers display cortico-striatal hypersensitivity to extreme gambles

SV Gelskov, KH Madsen, TZ Ramsøy, HR Siebner - NeuroImage, 2016 - Elsevier
Pathological gambling is an addictive disorder characterized by an irresistible urge to
gamble despite severe consequences. One of the hallmarks of pathological gambling is …

Neural and neurochemical basis of reinforcement-guided decision making

A Khani, G Rainer - Journal of neurophysiology, 2016 - journals.physiology.org
Decision making is an adaptive behavior that takes into account several internal and
external input variables and leads to the choice of a course of action over other available …

Recording extracellular neural activity in the behaving monkey using a semichronic and high-density electrode system

G Mendoza, A Peyrache, J Gámez… - Journal of …, 2016 - journals.physiology.org
We describe a technique to semichronically record the cortical extracellular neural activity in
the behaving monkey employing commercial high-density electrodes. After the design and …