Advancements in zebrafish applications for 21st century toxicology
GR Garcia, PD Noyes, RL Tanguay - Pharmacology & therapeutics, 2016 - Elsevier
The zebrafish model is the only available high-throughput vertebrate assessment system,
and it is uniquely suited for studies of in vivo cell biology. A sequenced and annotated …
and it is uniquely suited for studies of in vivo cell biology. A sequenced and annotated …
Using zebrafish in systems toxicology for developmental toxicity testing
Y Nishimura, A Inoue, S Sasagawa… - Congenital …, 2016 - Wiley Online Library
With the high cost and the long‐term assessment of developmental toxicity testing in
mammals, the vertebrate zebrafish has become a useful alternative model organism for high …
mammals, the vertebrate zebrafish has become a useful alternative model organism for high …
Heteroleptic mononuclear compounds of ruthenium (ii): Synthesis, structural analyses, in vitro antitumor activity and in vivo toxicity on zebrafish embryos
OA Lenis-Rojas, AR Fernandes… - Dalton …, 2016 - pubs.rsc.org
The limitations of platinum complexes in cancer treatment have motivated the extensive
investigation into other metal complexes such as ruthenium. We herein present the …
investigation into other metal complexes such as ruthenium. We herein present the …
Screening of Toxic Effects of Bisphenol A and Products of Its Degradation: Zebrafish (Danio rerio) Embryo Test and Molecular Docking
K Makarova, P Siudem, K Zawada, J Kurkowiak - Zebrafish, 2016 - liebertpub.com
Bisphenol A (BPA) acts as an endocrine-disrupting compound even at a low concentration.
Degradation of BPA could lead to the formation of toxic products. In this study, we compare …
Degradation of BPA could lead to the formation of toxic products. In this study, we compare …
The Complete and Updated
C Lawrence, J Best, J Cockington, EC Henry… - JoVE (Journal of …, 2016 - jove.com
The zebrafish (Danio rerio) is a model organism of increasing importance in many fields of
science. One of the most demanding technical aspects of culture of this species in the …
science. One of the most demanding technical aspects of culture of this species in the …
Hazard assessment of polycyclic aromatic hydrocarbons in water and sediment in the vicinity of coalmines
Purpose Rivers feeding into the Loskop Dam, South Africa, pass through coal mining and
heavily industrialised areas. Previous studies investigating mass mortalities of crocodile and …
heavily industrialised areas. Previous studies investigating mass mortalities of crocodile and …
环境毒理学研究的重要模式生物--斑马鱼
孙冰, 许慧慧, 黄超, 丁训城, 李卫华, 胡晶莹 - 环境与职业医学, 2016 - cqvip.com
斑马鱼被广泛应用于环境化学物的监测与评价, 并得到经济合作发展组织(OECD),
国际标准化组织(ISO) 等权威机构的认可. 本文简述了斑马鱼应用于环境毒理学研究的诸多优势 …
国际标准化组织(ISO) 等权威机构的认可. 本文简述了斑马鱼应用于环境毒理学研究的诸多优势 …
Osteogenic Differentiation of Human Embryonic Stem Cell-Derived Mesenchymal Progenitor Cells as a Model for Assessing Developmental Bone Toxicity In Vitro
D Sittner, B Huhse, M Steinfath, A Luch… - Applied In Vitro …, 2016 - liebertpub.com
The assessment of adverse effects of substances on human embryonic bone formation is an
integral part of regulatory in vivo studies that cover prenatal developmental toxicity. One of …
integral part of regulatory in vivo studies that cover prenatal developmental toxicity. One of …
Development of a quantitative morphological assessment of toxicant‐treated zebrafish larvae using brightfield imaging and high‐content analysis
S Deal, J Wambaugh, R Judson… - Journal of Applied …, 2016 - Wiley Online Library
One of the rate‐limiting procedures in a developmental zebrafish screen is the
morphological assessment of each larva. Most researchers opt for a time‐consuming …
morphological assessment of each larva. Most researchers opt for a time‐consuming …
In vitro screening methods for developmental toxicology
RG Ellis-Hutchings, E de Jong… - Developmental and …, 2016 - taylorfrancis.com
Traditional mammalian in vivo assays directed at characterizing the hazard potential of a test
agent during the development of an embryo are intensive in time, technical resources …
agent during the development of an embryo are intensive in time, technical resources …