Objectives Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease, which
affects synovial tissue in multiple joints. Although conventional treatments of RA commonly …

Certain nutritional components influence the cellular metabolism and interfere in the
pathological inflammatory process, so that they may act as a coadjuvant in the treatment of …

Successful gene therapy of neurological disorders is predicated on achieving widespread
and uniform transgene expression throughout the affected disease area in the brain …

Abstract The interleukin (IL)-1 family of cytokines comprises 11 members, including 7 pro-
inflammatory cytokines (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 anti …

Introduction: Targeted therapies have gained popularity in the treatment of several oncologic
and immune-mediated diseases. Immunosuppression caused by these drugs has been …

Objective The migration of health care toward a consumer‐driven system favors increased
patient participation during the treatment decision‐making process. Patient involvement in …

Background. Imprecision in estimates of benefits and harms around treatment choices is
rarely described to patients. Variation in sampling error between treatment alternatives (eg …

Background: Rheumatoid arthritis (RA) is an immune mediated joint-based chronic
inflammatory disorder recognized by joint inflammation, destruction, pain and remission …

Objective. We analyzed remission rates at 3 and 12 months in patients with rheumatoid
arthritis (RA) who were naive for disease-modifying antirheumatic drugs (DMARD) and who …

FXF is a third-generation antihistamine drug and osthole is assumed a natural antihistamine
alternative. This paper compares peripheral blood mononuclear cell (PBMC) incubation with …