The thermodynamics and kinetics of DNA hybridization, ie the process of self-assembly of
one, two or more complementary nucleic acid strands, has been studied for many years. The …

In this work, we attempt to apply a coarse-grained (CG) model, which is based on
anisotropic Gay–Berne and electric multipole (EMP) potentials, to the modeling of nucleic …

Advances in Chemical Physics, Volume 160 ADVANCES IN CHEMICAL PHYSICS Volume
160 Page 2 ADVANCES IN CHEMICAL PHYSICS Volume 160 Series Editors STUART A …

In this paper we study how varying oligonucleic acid backbone chemistry affects the
hybridization/melting thermodynamics of oligonucleic acids. We first describe the coarse …

The antineoplastic and antibiotic natural product mithramycin (MTM) is used against cancer-
related hypercalcemia and, experimentally, against Ewing sarcoma and lung cancers. MTM …

A DNA-based approach allows external control over the self-assembly process of tobacco
mosaic virus (TMV)-like ribonucleoprotein nanotubes: their growth from viral coat protein …

Rapid and quantitative detection of the binding of nucleic acids to surface-immobilized
probes remains a challenge in many biomedical applications. We investigated the …

The flexibility of short DNA fragments is studied by a Hamiltonian model which treats the
inter-strand and intra-strand forces at the level of the base pair. The elastic response of a set …

To form secondary structure, nucleic acids (NAs) must overcome electrostatic strand–strand
repulsion, which is moderated by the surrounding atmosphere of screening ions. The free …

Primer design represents a widely employed gambit in diverse molecular applications
including PCR, sequencing and probe hybridization. Variations of PCR, including primer …