Multiple sclerosis: genetics, biomarkers, treatments
Breakthroughs in the field of multiple sclerosis have led to a better understanding of the
physiopathology of the disease, follow up, and treatment of the patients that develop …
physiopathology of the disease, follow up, and treatment of the patients that develop …
Precision medicine in multiple sclerosis: biomarkers for diagnosis, prognosis, and treatment response
M Comabella, J Sastre-Garriga… - Current opinion in …, 2016 - journals.lww.com
Precision medicine in multiple sclerosis: biomarkers for dia... : Current Opinion in Neurology
Precision medicine in multiple sclerosis: biomarkers for diagnosis, prognosis, and treatment …
Precision medicine in multiple sclerosis: biomarkers for diagnosis, prognosis, and treatment …
Cerebrospinal fluid neurogranin and YKL‐40 as biomarkers of Alzheimer's disease
S Janelidze, J Hertze, H Zetterberg… - Annals of clinical …, 2016 - Wiley Online Library
Objective Widespread implementation of cerebrospinal fluid (CSF) biomarkers of
Alzheimer's disease (AD) in clinical settings requires improved accuracy for diagnosis of …
Alzheimer's disease (AD) in clinical settings requires improved accuracy for diagnosis of …
Neurofilament light chain level is a weak risk factor for the development of MS
G Arrambide, C Espejo, H Eixarch, LM Villar… - Neurology, 2016 - AAN Enterprises
Objective: To determine the prognostic value of selected biomarkers in clinically isolated
syndromes (CIS) for conversion to multiple sclerosis (MS) and disability accrual. Methods …
syndromes (CIS) for conversion to multiple sclerosis (MS) and disability accrual. Methods …
[HTML][HTML] Novel diagnostic cerebrospinal fluid biomarkers for pathologic subtypes of frontotemporal dementia identified by proteomics
CE Teunissen, N Elias, MJA Koel-Simmelink… - Alzheimer's & Dementia …, 2016 - Elsevier
Introduction Reliable cerebrospinal fluid (CSF) biomarkers enabling identification of
frontotemporal dementia (FTD) and its pathologic subtypes are lacking. Methods Unbiased …
frontotemporal dementia (FTD) and its pathologic subtypes are lacking. Methods Unbiased …
Cerebrospinal fluid chitinase‐3‐like 2 and chitotriosidase are potential prognostic biomarkers in early multiple sclerosis
M Møllgaard, M Degn, F Sellebjerg… - European journal of …, 2016 - Wiley Online Library
Background and purpose The role of chitinases and chitinase‐like proteins in multiple
sclerosis (MS) is currently unknown; however, cerebrospinal fluid (CSF) levels of chitinase 3 …
sclerosis (MS) is currently unknown; however, cerebrospinal fluid (CSF) levels of chitinase 3 …
Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German–Austrian retrospective multicenter study in patients with a clinically isolated …
AM Huss, S Halbgebauer, P Öckl, C Trebst, A Spreer… - Journal of …, 2016 - Springer
The majority of patients presenting with a first clinical symptom suggestive of multiple
sclerosis (MS) do not fulfill the MRI criteria for dissemination in space and time according to …
sclerosis (MS) do not fulfill the MRI criteria for dissemination in space and time according to …
Integration of metabolomics and proteomics in multiple sclerosis: From biomarkers discovery to personalized medicine
P Del Boccio, C Rossi, M di Ioia… - PROTEOMICS …, 2016 - Wiley Online Library
Personalized medicine is the science of individualized prevention and therapy. In the last
decade, advances in high‐throughput approaches allowed the development of proteomic …
decade, advances in high‐throughput approaches allowed the development of proteomic …
Glial and neuronal markers in cerebrospinal fluid in different types of multiple sclerosis
MA Mañé-Martínez, B Olsson, L Bau, E Matas… - Journal of …, 2016 - Elsevier
In the present study, CSF concentrations of NFL, t-tau, p-tau, GFAP, S-100B, YKL-40, MCP-
1, α-sAPP, β-sAPP, and Aβ38, Aβ40, Aβ42 were measured in 324 MS patients to test …
1, α-sAPP, β-sAPP, and Aβ38, Aβ40, Aβ42 were measured in 324 MS patients to test …
[HTML][HTML] Changes in serum ceruloplasmin levels based on immunomodulatory treatments and melatonin supplementation in multiple sclerosis patients
M Adamczyk-Sowa, P Sowa, S Mucha… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
Background The cause of multiple sclerosis (MS) is currently unknown, but it is thought that
oxidative damage and iron metabolism mechanisms are involved. The aim of this study was …
oxidative damage and iron metabolism mechanisms are involved. The aim of this study was …