Epigenetic inheritance of acquired traits through sperm RNAs and sperm RNA modifications
Once deemed heretical, emerging evidence now supports the notion that the inheritance of
acquired characteristics can occur through ancestral exposures or experiences and that …
acquired characteristics can occur through ancestral exposures or experiences and that …
Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification
While N6‐methyladenosine (m6A) is a well‐known epigenetic modification in bacterial DNA,
it remained largely unstudied in eukaryotes. Recent studies have brought to fore its potential …
it remained largely unstudied in eukaryotes. Recent studies have brought to fore its potential …
Transcriptome-wide distribution and function of RNA hydroxymethylcytosine
Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that
hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in …
hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in …
NSUN3 and ABH1 modify the wobble position of mt‐tRNAMet to expand codon recognition in mitochondrial translation
S Haag, KE Sloan, N Ranjan, AS Warda… - The EMBO …, 2016 - embopress.org
Mitochondrial gene expression uses a non‐universal genetic code in mammals. Besides
reading the conventional AUG codon, mitochondrial (mt‐) tRNAM et mediates incorporation …
reading the conventional AUG codon, mitochondrial (mt‐) tRNAM et mediates incorporation …
The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion
D Kao, AG Lai, E Stamataki, S Rosic, N Konstantinides… - elife, 2016 - elifesciences.org
The amphipod crustacean Parhyale hawaiensis is a blossoming model system for studies of
developmental mechanisms and more recently regeneration. We have sequenced the …
developmental mechanisms and more recently regeneration. We have sequenced the …
Post-transcriptional modifications in development and stem cells
Cells adapt to their environment by linking external stimuli to an intricate network of
transcriptional, post-transcriptional and translational processes. Among these, mechanisms …
transcriptional, post-transcriptional and translational processes. Among these, mechanisms …
Epigenomics in marine fishes
DCH Metzger, PM Schulte - Marine Genomics, 2016 - Elsevier
Epigenetic mechanisms are an underappreciated and often ignored component of an
organism's response to environmental change and may underlie many types of phenotypic …
organism's response to environmental change and may underlie many types of phenotypic …
The emerging epitranscriptomics of long noncoding RNAs
The pervasive transcription of genomes into long noncoding RNAs has been amply
demonstrated in recent years and garnered much attention. Similarly, emerging …
demonstrated in recent years and garnered much attention. Similarly, emerging …
Inhibitors of DNA methylation, histone deacetylation, and histone demethylation: a perfect combination for cancer therapy
CA Zahnow, M Topper, M Stone… - Advances in cancer …, 2016 - Elsevier
Epigenetic silencing and inappropriate activation of gene expression are frequent events
during the initiation and progression of cancer. These events involve a complex interplay …
during the initiation and progression of cancer. These events involve a complex interplay …
DNA methyltransferases exhibit dynamic expression during spermatogenesis
F Uysal, G Akkoyunlu, S Ozturk - Reproductive biomedicine online, 2016 - Elsevier
DNA methylation is one of the epigenetic marks and plays critically important functions
during spermatogenesis in mammals. DNA methylation is catalysed by DNA …
during spermatogenesis in mammals. DNA methylation is catalysed by DNA …