Polycations and their biomedical applications

K Kim, WCW Chen, Y Heo, Y Wang - Progress in Polymer Science, 2016 - Elsevier
Polycations are useful delivery vehicles for nucleic acids and proteins. Physicochemical
properties, safety, and cost are important design parameters for polycation-enabled …

The role of adipocytes in tissue regeneration and stem cell niches

B Shook, G Rivera Gonzalez, S Ebmeier… - Annual review of cell …, 2016 - annualreviews.org
Classically, white adipose tissue (WAT) was considered an inert component of connective
tissue but is now appreciated as a major regulator of metabolic physiology and endocrine …

EGF and curcumin co-encapsulated nanoparticle/hydrogel system as potent skin regeneration agent

X Li, X Ye, J Qi, R Fan, X Gao, Y Wu… - International journal …, 2016 - Taylor & Francis
Wound healing is a complex multifactorial process that relies on coordinated signaling
molecules to succeed. Epidermal growth factor (EGF) is a mitogenic polypeptide that …

Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival

A Mangraviti, SY Tzeng, D Gullotti, KL Kozielski, JE Kim… - Biomaterials, 2016 - Elsevier
There is a need for enabling non-viral nanobiotechnology to allow safe and effective gene
therapy and cell therapy, which can be utilized to treat devastating diseases such as brain …

[HTML][HTML] Regulating stem cell secretome using injectable hydrogels with in situ network formation

L Cai, RE Dewi, AB Goldstone, JE Cohen… - Advanced healthcare …, 2016 - ncbi.nlm.nih.gov
A family of Shear-thinning Hydrogels for Injectable Encapsulation and Long-term Delivery
(SHIELD) has been designed and synthesized with controlled in situ stiffening properties to …

Nanoparticle-mediated transcriptional modification enhances neuronal differentiation of human neural stem cells following transplantation in rat brain

X Li, SY Tzeng, X Liu, M Tammia, YH Cheng, A Rolfe… - Biomaterials, 2016 - Elsevier
Strategies to enhance survival and direct the differentiation of stem cells in vivo following
transplantation in tissue repair site are critical to realizing the potential of stem cell-based …

Nanoparticle-mediated conversion of primary human astrocytes into neurons and oligodendrocytes

X Li, K Kozielski, YH Cheng, H Liu, CG Zamboni… - Biomaterials …, 2016 - pubs.rsc.org
Central nervous system (CNS) diseases and injuries are accompanied by reactive gliosis
and scarring involving the activation and proliferation of astrocytes to form hypertrophic and …

Bioreducible cationic poly (amido amine) s for enhanced gene delivery and osteogenic differentiation of tonsil-derived mesenchymal stem Cells

H Jeong, ES Lee, G Jung, J Park… - Journal of …, 2016 - ingentaconnect.com
The development of efficient and safe gene delivery carriers has been a major challenge in
the clinical application of non-viral gene therapy. Herein, we report novel bioreducible poly …

Effects of cold stimulation on mitochondrial activity and VEGF expression in vitro

T Sugasawa, N Mukai, K Tamura… - … Journal of Sports …, 2016 - thieme-connect.com
We aimed to clarify the effects of cold stimulation at various temperatures on mitochondrial
activity and vascular endothelial growth factor (VEGF) expression in vitro. Human fibroblast …

Vascular endothelial growth factor 165-transfected adipose-derived mesenchymal stem cells promote vascularization-assisted fat transplantation

C Jun-Jiang, X Huan-Jiu - Artificial Cells, Nanomedicine, and …, 2016 - Taylor & Francis
Objective: To investigate the effect of vascular endothelial growth factor 165 (VEGF165) and
adipose-derived mesenchymal stem cells (ASCs) in promoting the survival of fat grafts, and …