[HTML][HTML] Molecular and clinical significance of fibroblast growth factor 2 (FGF2/bFGF) in malignancies of solid and hematological cancers for personalized therapies

MR Akl, P Nagpal, NM Ayoub, B Tai, SA Prabhu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Fibroblast growth factor (FGF) signaling is essential for normal and cancer biology.
Mammalian FGF family members participate in multiple signaling pathways by binding to …

Altered FGF signalling in congenital craniofacial and skeletal disorders

S Moosa, B Wollnik - Seminars in cell & developmental biology, 2016 - Elsevier
The fibroblast growth factor (FGF) signalling pathway has been the focus of intense genetic
and functional research for several decades. The emerging data implicate FGF signalling in …

Gas-phase analysis of the complex of fibroblast growthfactor 1 with heparan sulfate: a traveling wave ion mobility spectrometry (TWIMS) and molecular modeling study

Y Zhao, A Singh, Y Xu, C Zong, F Zhang… - Journal of the …, 2016 - ACS Publications
Fibroblast growth factors (FGFs) regulate several cellular developmental processes by
interacting with cell surface heparan proteoglycans and transmembrane cell surface …

[HTML][HTML] Muenke syndrome

P Kruszka, YA Addissie, NB Agochukwu, ES Doherty… - 2016 - europepmc.org
Muenke syndrome is defined by the presence of the specific FGFR3 pathogenic variant–c.
749C> G–that results in the protein change p. Pro250Arg. Muenke syndrome is …

Expansion of the variable expression of Muenke syndrome: Hydrocephalus without craniosynostosis

A González‐del Angel… - American Journal of …, 2016 - Wiley Online Library
Muenke syndrome (MS) is an autosomal dominant coronal craniosynostosis syndrome with
variable extracranial anomalies. We studied 56 unrelated patients with non‐syndromic uni …

Craniosynostosis: current conceptions and misconceptions

CSR Fonteles, RH Finnell, TM George… - Aims …, 2016 - thieme-connect.com
Cranial bones articulate in areas called sutures that must remain patent until skull growth is
complete. Craniosynostosis is the condition that results from premature closure of one or …