Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a
major etiological agent for multiple severe malignancies in immune-compromised patients …

Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus
(KSHV), is a malignant human oncovirus belonging to the gamma herpesvirus family. HHV-8 …

The host intracellular antiviral restriction factors inhibit viral infection and replication. The 5′-
AMP-activated protein kinase (AMPK) is a cellular energy sensor regulating metabolic …

CTHRC1 (collagen triple-helix repeat-containing 1), a protein secreted during the tissue-
repair process, is highly expressed in several malignant tumors, including pancreatic …

Highlights•KSHV may not transform human endothelial cells in the same manner as
'classical'oncogenic viruses.•KSHV may act through a combination of proliferative …

Essentials• Mechanism of thrombin–induced inflammation is not fully understood.• Thrombin
induced monocyte adhesion and barrier loss require Angiopoietin‐2 (Ang‐2).• Ang‐2 …

Kaposi's sarcoma (KS) is a highly angiogenic and inflammatory neoplasia. The angiogenic
and inflammatory cytokine angiopoietin-2 (Ang-2) is strongly expressed in KS due to …

Abstract Kaposi's Sarcoma (KS), is a vascular tumor of endothelial cells caused by the
infection of herpesvirus Kaposi's Sarcoma Herpesvirus (KSHV). It is primarily found in HIV …