Many modern human genomes retain DNA inherited from interbreeding with archaic
hominins, such as Neandertals, yet the influence of this admixture on human traits is largely …

Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. To
identify new susceptibility loci, we performed meta-analysis on genome-wide association …

We performed genome-wide meta-analysis of lipid traits on three samples of Mexican and
Mexican American ancestry comprising 4,383 individuals and followed up significant and …

Parkinson's disease (PD) is the most common cause of neurodegenerative movement
disorder and the second most common cause of dementia. Genes are thought to have a …

Transcription factors bind to the genome by forming specific contacts with the primary DNA
sequence; however, RNA-binding proteins (RBPs) have greater scope to achieve binding …

Survival following a diagnosis of multiple myeloma (MM) varies between patients and some
of these differences may be a consequence of inherited genetic variation. In this study, to …

Childhood acute lymphoblastic leukemia (ALL) occurs more frequently in males. Reasons
behind sex differences in childhood ALL risk are unknown. In the present genome-wide …

Background: There has been increasing interest in oxytocin (peptide: OT, gene: OXT) as a
treatment pathway for neurodevelopmental disorders such as Autism Spectrum Disorder …

Functionally altered biological mechanisms arising from disease-associated polymorphisms,
remain difficult to characterise when those variants are intergenic, or, fall between genes …

We performed a Phenome-Wide Association Study (PheWAS) to identify interrelationships
between the immune system genetic architecture and a wide array of phenotypes from two …