Abstract Diabetic foot ulcers affect 15–20% of all diabetic patients and remain an important
challenge since the available therapies have limited efficacy and some of the novel …

The presence of peripheral arterial disease (PAD) is an important consideration in the
management of diabetic foot ulcers. Indeed, arteriopathy is a major factor in delayed healing …

Context: Circulating cells, including endothelial progenitor cells (EPCs) and monocyte
subtypes, are involved in diabetic complications. Modulation of these cells may mediate …

Rationale: Peripheral arterial disease (PAD) is a clinical manifestation of extracoronary
atherosclerosis. Despite sharing the same risk factors, only 20% to 30% of patients with …

Angiotensin-converting enzymes, ACE and ACE2, are key members of renin angiotensin
system. Activation of ACE2/Ang-(1-7) pathway enhances cardiovascular protective functions …

Air pollution is a major challenge to public health. Ambient fine particulate matter (PM) is the
key component for air pollution, and associated with significant mortality. The majority of the …

The role of endothelial progenitor cells (EPCs) in peripheral artery disease (PAD) remains
unclear. We hypothesized that EPC mobilization and function play a central role in the …

Background Proprotein convertase subtilisin/kexin type 9 (PCSK 9) is involved in cholesterol
homeostasis, inflammation, and oxidative stress. This study investigated the association of …

Background Blood outgrowth endothelial cells (BOEC s) mediate therapeutic
neovascularization in experimental models, but outgrowth characteristics and functionality of …

Cancer conveys profound social and economic consequences throughout the world.
Metastasis is responsible for approximately 90% of cancer-associated mortality and, when it …