Patient global assessment in measuring disease activity in rheumatoid arthritis: a review of the literature
E Nikiphorou, H Radner, K Chatzidionysiou… - Arthritis research & …, 2016 - Springer
Patient-reported outcomes (PROs) reflect the patient's perspective and are used in
rheumatoid arthritis (RA) routine clinical practice. Patient global assessment (PGA) is one of …
rheumatoid arthritis (RA) routine clinical practice. Patient global assessment (PGA) is one of …
Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia
Purpose Sarcopenia is an age-related muscle condition which is frequently a precursor of
frailty, mobility disability and premature death. It has a high prevalence in older populations …
frailty, mobility disability and premature death. It has a high prevalence in older populations …
Efficacy and safety of ABT‐494, a selective JAK‐1 inhibitor, in a phase IIb study in patients with rheumatoid arthritis and an inadequate response to methotrexate
MC Genovese, JS Smolen, ME Weinblatt… - Arthritis & …, 2016 - Wiley Online Library
Objective To evaluate the efficacy and safety of ABT‐494, a selective JAK‐1 inhibitor, in
patients with moderate‐to‐severe rheumatoid arthritis (RA) and an inadequate response to …
patients with moderate‐to‐severe rheumatoid arthritis (RA) and an inadequate response to …
Targeting ultrasound remission in early rheumatoid arthritis: the results of the TaSER study, a randomised clinical trial
J Dale, A Stirling, R Zhang, D Purves, J Foley… - Annals of the …, 2016 - ard.bmj.com
Objective To investigate whether an intensive early rheumatoid arthritis (RA) treat-to-target
(T2T) strategy could be improved through the use of musculoskeletal ultrasound (MSUS) …
(T2T) strategy could be improved through the use of musculoskeletal ultrasound (MSUS) …
[PDF][PDF] A phase IIb study of ABT‐494, a selective JAK‐1 inhibitor, in patients with rheumatoid arthritis and an inadequate response to anti–tumor necrosis factor therapy
JM Kremer, P Emery, HS Camp… - Arthritis & …, 2016 - Wiley Online Library
Objective To compare the efficacy and safety of ABT‐494, a novel selective JAK‐1 inhibitor,
with placebo in patients with moderate‐to‐severe rheumatoid arthritis (RA) and an …
with placebo in patients with moderate‐to‐severe rheumatoid arthritis (RA) and an …
Patient‐physician discordance in global assessment in rheumatoid arthritis: a systematic literature review with meta‐analysis
C Desthieux, A Hermet, B Granger… - Arthritis care & …, 2016 - Wiley Online Library
Objective The integration of the patient in therapeutic decision‐making is important in the
management of rheumatoid arthritis (RA), but the patient opinion regarding disease status …
management of rheumatoid arthritis (RA), but the patient opinion regarding disease status …
[HTML][HTML] Inflammatory glycoproteins in cardiometabolic disorders, autoimmune diseases and cancer
MA Connelly, EG Gruppen, JD Otvos, RPF Dullaart - Clinica chimica acta, 2016 - Elsevier
The physiological function initially attributed to the oligosaccharide moieties or glycans on
inflammatory glycoproteins was to improve protein stability. However, it is now clear that …
inflammatory glycoproteins was to improve protein stability. However, it is now clear that …
Sarilumab plus methotrexate improves patient-reported outcomes in patients with active rheumatoid arthritis and inadequate responses to methotrexate: results of a …
V Strand, M Kosinski, CI Chen, G Joseph… - Arthritis research & …, 2016 - Springer
Background Sarilumab is a human monoclonal antibody directed against the alpha subunit
of the interleukin-6 receptor complex. In the MOBILITY phase III randomized controlled trial …
of the interleukin-6 receptor complex. In the MOBILITY phase III randomized controlled trial …
A prospective, randomized, double‐blind, multicentre, parallel‐group, active controlled study to compare efficacy and safety of biosimilar adalimumab (Exemptia; ZRC …
RH Jani, R Gupta, G Bhatia, G Rathi… - International Journal …, 2016 - Wiley Online Library
Aim In this study, efficacy, tolerability and safety of biosimilar adalimumab (Exemptia; Zydus
Cadila) was compared with reference adalimumab (Humira; AbbVie) in patients with …
Cadila) was compared with reference adalimumab (Humira; AbbVie) in patients with …
Tofacitinib versus methotrexate in rheumatoid arthritis: patient-reported outcomes from the randomised phase III ORAL Start trial
Objectives To compare patient-reported outcomes (PROs) in methotrexate (MTX)-naive
patients (defined as no prior treatment or≤ 3 doses) receiving tofacitinib versus MTX …
patients (defined as no prior treatment or≤ 3 doses) receiving tofacitinib versus MTX …