Pericytes of the neurovascular unit: key functions and signaling pathways

MD Sweeney, S Ayyadurai, BV Zlokovic - Nature neuroscience, 2016 - nature.com
Pericytes are vascular mural cells embedded in the basement membrane of blood
microvessels. They extend their processes along capillaries, pre-capillary arterioles and …

Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy

AR Cantelmo, LC Conradi, A Brajic, J Goveia… - Cancer cell, 2016 - cell.com
Abnormal tumor vessels promote metastasis and impair chemotherapy. Hence, tumor vessel
normalization (TVN) is emerging as an anti-cancer treatment. Here, we show that tumor …

Discovering cardiac pericyte biology: From physiopathological mechanisms to potential therapeutic applications in ischemic heart disease

E Avolio, P Madeddu - Vascular pharmacology, 2016 - Elsevier
Microvascular pericytes and the more recently discovered adventitial pericyte-like progenitor
cells are a subpopulation of vascular stem cells closely associated with small and large …

Angiomotin like-1 is a novel component of the N-cadherin complex affecting endothelial/pericyte interaction in normal and tumor angiogenesis

Y Zheng, Y Zhang, G Barutello, K Chiu, M Arigoni… - Scientific reports, 2016 - nature.com
Transmission of mechanical force via cell junctions is an important component that molds
cells into shapes consistent with proper organ function. Of particular interest are the …