Reduced cohesin destabilizes high-level gene amplification by disrupting pre-replication complex bindings in human cancers with chromosomal instability
J Yun, SH Song, JY Kang, J Park, HP Kim… - Nucleic acids …, 2016 - academic.oup.com
Gene amplification is a hallmark of cancer with chromosomal instability although the
underlying mechanism by which altered copy numbers are maintained is largely unclear …
underlying mechanism by which altered copy numbers are maintained is largely unclear …
[HTML][HTML] A mechanism for 1, 4-Benzoquinone-induced genotoxicity
Benzene is a common environmental toxin and its metabolite, 1-4-Benzoquinone (BQ)
causes hematopoietic cancers like myelodysplastic syndrome (MDS) and acute myeloid …
causes hematopoietic cancers like myelodysplastic syndrome (MDS) and acute myeloid …
Cytotoxic effects of novel small molecules on PC3 prostate cancer cells
P Udompholkul - 2016 - search.proquest.com
Prostate cancer (PCa) is the most common cancer among men and is the second leading
cause of cancer-related deaths in males in the United States and Europe. PCa is more …
cause of cancer-related deaths in males in the United States and Europe. PCa is more …
Dynamic higher-order chromatin structure mediated by cohesin complex contributes to tumor development
윤지연 - 2016 - s-space.snu.ac.kr
Higher-order chromatin architecture is known to be important to gene regulation during
hematopoiesis, erythropoiesis, and development. Chromatin architectural molecule cohesin …
hematopoiesis, erythropoiesis, and development. Chromatin architectural molecule cohesin …