[HTML][HTML] Therapeutic options for management of endometrial hyperplasia
V Chandra, JJ Kim, DM Benbrook… - Journal of …, 2016 - synapse.koreamed.org
Endometrial hyperplasia (EH) comprises a spectrum of changes in the endometrium ranging
from a slightly disordered pattern that exaggerates the alterations seen in the late …
from a slightly disordered pattern that exaggerates the alterations seen in the late …
Metformin use and gynecological cancers: a novel treatment option emerging from drug repositioning
A Gadducci, N Biglia, R Tana, S Cosio… - Critical reviews in oncology …, 2016 - Elsevier
Metformin exerts antitumor effects mainly through AMP-activated protein kinase [AMPK]
activation and phosphatidylinositol 3-kinase [PI3K]-Akt-mammalian target of rapamycin …
activation and phosphatidylinositol 3-kinase [PI3K]-Akt-mammalian target of rapamycin …
Molecular characterization of insulin resistance and glycolytic metabolism in the rat uterus
Y Zhang, X Sun, X Sun, F Meng, M Hu, X Li, W Li… - Scientific reports, 2016 - nature.com
Peripheral insulin resistance and hyperandrogenism are the primary features of polycystic
ovary syndrome (PCOS). However, how insulin resistance and hyperandrogenism affect …
ovary syndrome (PCOS). However, how insulin resistance and hyperandrogenism affect …
Hormones and endometrial carcinogenesis
Endometrial cancer (EC) is the commonest gynaecological cancer in the Western World with
an alarmingly increasing incidence related to longevity and obesity. Ovarian hormones …
an alarmingly increasing incidence related to longevity and obesity. Ovarian hormones …
Intravaginal administration of metformin hydrochloride loaded cationic niosomes amalgamated with thermosensitive gel for the treatment of polycystic ovary syndrome …
N Saini, RK Sodhi, L Bajaj, RS Pandey, UK Jain… - Colloids and Surfaces B …, 2016 - Elsevier
Background and objective Metformin hydrochloride (MTF-HCl) is extensively recommended
by physicians for the treatment of polycystic ovary syndrome (PCOS). Mechanistically, MTF …
by physicians for the treatment of polycystic ovary syndrome (PCOS). Mechanistically, MTF …
Effect of oral versus intrauterine progestins on weight in women undergoing fertility preserving therapy for complex atypical hyperplasia or endometrial cancer
D Cholakian, K Hacker, AN Fader, PA Gehrig… - Gynecologic …, 2016 - Elsevier
Objective The objective of this analysis was to evaluate weight changes associated with oral
progestin therapies versus the levonorgestrel-containing intrauterine device (LNG-IUD) in …
progestin therapies versus the levonorgestrel-containing intrauterine device (LNG-IUD) in …
Proliferation and metastatic potential of endometrial cancer cells in response to metformin treatment in a high versus normal glucose environment
A de Barros Machado, V Dos Reis… - Oncology …, 2016 - spandidos-publications.com
In order to improve our understanding of the potential preventive and therapeutic role of
metformin, the present study aimed to investigate the capability of low‑dose metformin in the …
metformin, the present study aimed to investigate the capability of low‑dose metformin in the …