Cancer immunotherapy has entered in a new era with the development of first-generation
immune checkpoint inhibitors targeting the PD1/PD-L1 and CTLA-4 pathways. In this …

Men of African origin are disproportionately affected by prostate cancer: prostate cancer
incidence is highest among men of African origin in the USA, prostate cancer mortality is …

Background Robust data on patient-reported outcome measures comparing treatments for
clinically localized prostate cancer are lacking. We investigated the effects of active …

Prostate cancer is a significant public health burden and a major cause of morbidity and
mortality among men worldwide. Analyzing geographic patterns and temporal trends may …

Background Prostate cancer can negatively impact quality of life of the patient and his
spouse caregiver, but interventions rarely target the health of both partners simultaneously …

Cancer related fatigue (CRF) is a common and debilitating symptom that can influence
quality of life (QoL) in cancer patients. The increase in survival times stresses for a better …

Context Radical prostatectomy is the most common reason for male stress urinary
incontinence. There is still uncertainty about its diagnostic and therapeutic management …

Purpose Technical developments in the field of external beam radiation therapy (RT)
enabled the clinical introduction of image guided intensity modulated radiation therapy (IG …

Objectives To evaluate prospectively the associations between illness uncertainty, anxiety,
fear of progression and general and disease‐specific quality of life (QoL) in men with …

Background Radiomics or computer–extracted texture features have been shown to achieve
superior performance than multiparametric MRI (mpMRI) signal intensities alone in targeting …