[HTML][HTML] Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis

Y Xu, T Mizuno, A Sridharan, Y Du, M Guo, J Tang… - JCI insight, 2016 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease characterized by airway
remodeling, inflammation, alveolar destruction, and fibrosis. We utilized single-cell RNA …

Alveolar epithelial disintegrity in pulmonary fibrosis

T Kulkarni, J de Andrade, Y Zhou… - … of Physiology-Lung …, 2016 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by progressive
decline in lung function, resulting in significant morbidity and mortality. Current concepts of …

Precision medicine: the new frontier in idiopathic pulmonary fibrosis

R Brownell, N Kaminski, PG Woodruff… - American Journal of …, 2016 - atsjournals.org
Precision medicine is defined by the National Institute of Health's Precision Medicine
Initiative Working Group as an approach to disease treatment that takes into account …

Effect of M uc5b promoter polymorphism on disease predisposition and survival in idiopathic interstitial pneumonias

JJ van der Vis, R Snetselaar, KM Kazemier… - …, 2016 - Wiley Online Library
Background and objective A common polymorphism in the MUC5B gene (rs35705950) is
associated with susceptibility to idiopathic pulmonary fibrosis (IPF) and familial interstitial …

Interstitial lung disease in children younger than 2 years

P Spagnolo, A Bush - Pediatrics, 2016 - publications.aap.org
Childhood interstitial lung disease (chILD) comprises a large and heterogeneous group of
rare disorders characterized by diffuse pulmonary infiltrates, restrictive lung physiology, and …

Idiopathic pulmonary fibrosis: epidemiology, clinical features, prognosis, and management

JP Lynch III, RH Huynh, MC Fishbein… - … in respiratory and …, 2016 - thieme-connect.com
Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic interstitial lung pneumonia
associated with the histologic pattern of usual interstitial pneumonia (UIP). Although UIP is a …

[HTML][HTML] Metabolic functions of the lung, disorders and associated pathologies

A Alvarado, I Arce - Journal of clinical medicine research, 2016 - ncbi.nlm.nih.gov
The primary function of the lungs is gas exchange. Approximately 400 million years ago, the
Earth's atmosphere gained enough oxygen in the gas phase for the animals that emerged …

[PDF][PDF] Tumour markers in rheumatoid arthritis-associated interstitial lung disease

T Wang, XJ Zheng, YL Ji, ZA Liang… - Clin Exp …, 2016 - clinexprheumatol.org
Objective Interstitial lung disease (ILD) is the most common pulmonary extra-articular
manifestations of rheumatoid arthritis (RA), but the pathogenesis of RA-ILD is unknown. The …

The value of a multidisciplinary approach to the diagnosis of usual interstitial pneumonitis and idiopathic pulmonary fibrosis: radiology, pathology, and clinical …

JH Chung, DA Lynch - American Journal of Roentgenology, 2016 - Am Roentgen Ray Soc
OBJECTIVE. Multidisciplinary discussion is essential in establishing the diagnosis of
idiopathic pulmonary fibrosis (IPF) and in determining prognosis. CONCLUSION. The CT …

Pulmonary fibrosis on high-resolution CT of patients with pulmonary alveolar proteinosis

M Akira, Y Inoue, T Arai, C Sugimoto… - American Journal of …, 2016 - Am Roentgen Ray Soc
OBJECTIVE. The CT findings of pulmonary fibrosis in patients with pulmonary alveolar
proteinosis (PAP) are not yet well defined. The objective of this study was to evaluate the CT …