Nonsense-mediated mRNA decay in humans at a glance
T Kurosaki, LE Maquat - Journal of cell science, 2016 - journals.biologists.com
Nonsense-mediated mRNA decay (NMD) is an mRNA quality-control mechanism that
typifies all eukaryotes examined to date. NMD surveys newly synthesized mRNAs and …
typifies all eukaryotes examined to date. NMD surveys newly synthesized mRNAs and …
The exon junction complex as a node of post-transcriptional networks
HL Hir, J Saulière, Z Wang - Nature reviews Molecular cell biology, 2016 - nature.com
The exon junction complex (EJC) is deposited onto mRNAs following splicing and adopts a
unique structure, which can both stably bind to mRNAs and function as an anchor for diverse …
unique structure, which can both stably bind to mRNAs and function as an anchor for diverse …
Nonsense‐mediated mRNA decay: novel mechanistic insights and biological impact
ED Karousis, S Nasif… - Wiley Interdisciplinary …, 2016 - Wiley Online Library
Nonsense‐mediated mRNA decay (NMD) was originally coined to define a quality control
mechanism that targets mRNAs with truncated open reading frames due to the presence of a …
mechanism that targets mRNAs with truncated open reading frames due to the presence of a …
The antagonistic gene paralogs Upf3a and Upf3b govern nonsense-mediated RNA decay
EY Shum, SH Jones, A Shao, JN Chousal, MD Krause… - Cell, 2016 - cell.com
Gene duplication is a major evolutionary force driving adaptation and speciation, as it allows
for the acquisition of new functions and can augment or diversify existing functions. Here, we …
for the acquisition of new functions and can augment or diversify existing functions. Here, we …
Physiological and pathophysiological role of nonsense-mediated mRNA decay
F Ottens, NH Gehring - Pflügers Archiv-European Journal of Physiology, 2016 - Springer
Nonsense-mediated messenger RNA (mRNA) decay (NMD) is a quality control mechanism
that degrades irregular or faulty mRNAs. NMD mainly degrades mRNAs, which contain a …
that degrades irregular or faulty mRNAs. NMD mainly degrades mRNAs, which contain a …
Identification and characterisation of novel involved in the nonsense-mediated mRNA decay (NMD) pathway
A Casadio - 2016 - era.ed.ac.uk
Nonsense mediated mRNA decay (NMD) is a surveillance mechanism that targets
transcripts containing premature stop codons (PTCs) for degradation, and that also …
transcripts containing premature stop codons (PTCs) for degradation, and that also …