MEN1, MEN4, and carney complex: pathology and molecular genetics

MH Schernthaner-Reiter, G Trivellin… - Neuroendocrinology, 2016 - karger.com
Pituitary adenomas are a common feature of a subset of endocrine neoplasia syndromes,
which have otherwise highly variable disease manifestations. We provide here a review of …

Interplay between menin and Dnmt1 reversibly regulates pancreatic cancer cell growth downstream of the Hedgehog signaling pathway

P Cheng, Y Wang, G Li, S Yang, C Liu, H Hu, G Jin… - Cancer letters, 2016 - Elsevier
Menin, the product of the Men1 gene, which is frequently mutated in pancreatic
neuroendocrine tumors, acts as a chromatin-remodeling factor to modulate the transcription …

Menin localization in cell membrane compartment

X He, L Wang, J Yan, C Yuan, ES Witze… - Cancer biology & …, 2016 - Taylor & Francis
Menin is encoded by the MEN1 gene, which is mutated in an inherited human syndrome,
multiple endocrine neoplasia type 1 (MEN1). Menin is primarily nuclear protein, acting as a …

Синдром Золлингера-Эллисона

ИВ Маев, ДН Андреев, ЮА Кучерявый, ДТ Дичева… - 2016 - elibrary.ru
В настоящем учебном пособии представлен обзор, посвященный этиопатогенезу,
клиническим проявлениям, диагностическим методикам, а также лечению синдрома …

Die DEAD-Box RNA-Helikase DDX6 rekrutiert P-TEFb aus dem 7SK snRNP für die Inkorporation in den AF4-Superelongationskomplex

F Mück - 2016 - publikationen.ub.uni-frankfurt.de
Die eukaryotische RNA-Polymerase II (RNAPII) ist der zentrale Faktor für die Umsetzung
des genetischen Codes in funktionelle Proteine. Durch die Transkription wird die statische …