In vitro and in vivo antioxidant activity of polyphenols extracted from black highland barley

Y Shen, H Zhang, L Cheng, L Wang, H Qian, X Qi - Food Chemistry, 2016 - Elsevier
The objective of this study was to determine the antioxidant capacity of polyphenols
extracted from black highland barley (BHLPE) in vitro and in vivo. BHLPE was found to have …

Structure–activity relationship of antioxidant dipeptides: Dominant role of Tyr, Trp, Cys and Met residues

L Zheng, Y Zhao, H Dong, G Su, M Zhao - Journal of Functional Foods, 2016 - Elsevier
Antioxidant activities of amino acids and synthetic dipeptides were studied to elucidate the
structure–activity relationship of antioxidant dipeptides. Results showed that Tyr-and Trp …

Antioxidant mechanism of betaine without free radical scavenging ability

M Zhang, H Zhang, H Li, F Lai, X Li… - Journal of agricultural …, 2016 - ACS Publications
Betaine (BET) is a native compound widely studied as an antioxidant in agriculture and
human health. However, the antioxidant mechanism of BET remains unclear. In this …

Protective effects of kaempferol against reactive oxygen species-induced hemolysis and its antiproliferative activity on human cancer cells

W Liao, L Chen, X Ma, R Jiao, X Li, Y Wang - European Journal of …, 2016 - Elsevier
The protective effects of kaempferol against reactive oxygen species (ROS)-induced
hemolysis and its antiproliferative activity on human cancer cells were evaluated in this …

Efficacy and safety of prostaglandin E1 plus lipoic acid combination therapy versus monotherapy for patients with diabetic peripheral neuropathy

DQ Jiang, MX Li, YJ Ma, Y Wang, Y Wang - Journal of Clinical …, 2016 - Elsevier
The aim of this report was to evaluate the efficacy and safety of prostaglandin E1 (PGE1)
plus lipoic acid (LA) for the treatment of diabetic peripheral neuropathy (DPN) compared …

Novel walnut peptide–selenium hybrids with enhanced anticancer synergism: Facile synthesis and mechanistic investigation of anticancer activity

W Liao, R Zhang, C Dong, Z Yu… - International Journal of …, 2016 - Taylor & Francis
This contribution reports a facile synthesis of degreased walnut peptides (WP1)-
functionalized selenium nanoparticles (SeNPs) hybrids with enhanced anticancer activity …

Diosmetin prevents TGF-β1-induced epithelial-mesenchymal transition via ROS/MAPK signaling pathways

A Ge, Y Ma, YN Liu, YS Li, H Gu, JX Zhang, QX Wang… - Life Sciences, 2016 - Elsevier
Aims Epithelial-mesenchymal transition (EMT) plays a critical role in airway repair and
remodeling in many respiratory diseases such as asthma and pulmonary fibrosis. The …

[HTML][HTML] Diosmetin inhibits the metastasis of hepatocellular carcinoma cells by downregulating the expression levels of MMP‑2 and MMP‑9

J Liu, X Wen, B Liu, Q Zhang… - Molecular …, 2016 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most malignant types of tumor worldwide with
a high rate of mortality. Diosmetin (DIOS) exhibits various activities, including anticancer …

[HTML][HTML] Diosmetin inhibits cell proliferation and induces apoptosis by regulating autophagy via the mammalian target of rapamycin pathway in hepatocellular …

J Liu, H Ren, B Liu, Q Zhang, M Li… - Oncology …, 2016 - spandidos-publications.com
Hepatocellular carcinoma (HCC), which is a type of malignant tumor, is the fifth most
common cancer in men and ninth in women worldwide. The aim of the present study was to …

[HTML][HTML] Diosmetin triggers cell apoptosis by activation of the p53/Bcl-2 pathway and inactivation of the Notch3/NF-κB pathway in HepG2 cells

J Qiao, J Liu, K Jia, N Li, B Liu… - Oncology …, 2016 - spandidos-publications.com
Diosmetin (DIOS), a flavonoid compound, is abundant in Citrus limon. Emerging studies
have shown that DIOS is an effective compound implicated in multiple types of cancer …