DNA damage responses in mammalian oocytes

JK Collins, KT Jones - Reproduction, 2016 - rep.bioscientifica.com
Antiprogestins constitute a group of compounds, developed since the early 1980s, that bind
progesterone receptors with different affinities. The first clinical uses for antiprogestins were …

New insights into the role of ubiquitylation of proteins

GS McDowell, A Philpott - International review of cell and molecular …, 2016 - Elsevier
Posttranslational modification of proteins by the addition of ubiquitin and related modifiers
has an essential role in cellular processes such as protein degradation and subcellular …

Giraffe genome sequence reveals clues to its unique morphology and physiology

M Agaba, E Ishengoma, WC Miller, BC McGrath… - Nature …, 2016 - nature.com
The origins of giraffe's imposing stature and associated cardiovascular adaptations are
unknown. Okapi, which lacks these unique features, is giraffe's closest relative and provides …

DNA damage response and repair in mouse oocytes

J Collins - 2016 - eprints.soton.ac.uk
This thesis investigates the response of mouse oocytes to DNA damage, and their ability to
repair such damage. The effect on the progression through the first meiotic division is …