The mass production of redundant, misleading, and conflicted systematic reviews and meta‐analyses

JPA Ioannidis - The Milbank Quarterly, 2016 - Wiley Online Library
Policy Points: Currently, there is massive production of unnecessary, misleading, and
conflicted systematic reviews and meta‐analyses. Instead of promoting evidence‐based …

Individual participant data meta‐analyses compared with meta‐analyses based on aggregate data

CT Smith, M Marcucci, SJ Nolan, A Iorio… - Cochrane Database …, 2016 - cochranelibrary.com
Background Meta‐analyses based on individual participant data (IPD‐MAs) allow more
powerful and uniformly consistent analyses as well as better characterisation of subgroups …

[图书][B] Genomics and the reimagining of personalized medicine

R Tutton - 2016 - taylorfrancis.com
Drawing on insights from work in medical history and sociology, this book analyzes
changing meanings of personalized medicine over time, from the rise of biomedicine in the …

Antipsychotic medications for cocaine dependence

BI Indave, S Minozzi, PP Pani… - Cochrane Database of …, 2016 - cochranelibrary.com
Antipsychotic medications for cocaine dependence - Indave, BI - 2016 | Cochrane Library Skip
to Content Cookies Our site uses cookies to improve your experience. You can find out more …

Multiple imputation for IPD meta‐analysis: allowing for heterogeneity and studies with missing covariates

M Quartagno, JR Carpenter - Statistics in medicine, 2016 - Wiley Online Library
Recently, multiple imputation has been proposed as a tool for individual patient data meta‐
analysis with sporadically missing observations, and it has been suggested that within‐study …

Balneotherapy in rheumatoid arthritis—a systematic review

I Santos, P Cantista, C Vasconcelos - International journal of …, 2016 - Springer
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
persistent inflammation of synovial joints with pain, often leading to joint destruction and …

N-of-1 trials can be aggregated to generate group mean treatment effects: a systematic review and meta-analysis

S Punja, D Xu, CH Schmid, L Hartling, L Urichuk… - Journal of clinical …, 2016 - Elsevier
Objectives To evaluate how data from n-of-1 trials may be used in systematic reviews and
meta-analyses by examining the effects of amphetamine and methylphenidate for attention …

Beyond advocacy: making space for conservation scientists in public debate

GE Garrard, F Fidler, BC Wintle, YE Chee… - Conservation …, 2016 - Wiley Online Library
The topic of advocacy by scientists has been debated for decades, yet there is little
agreement about whether scientists can or should be advocates. The fear of crossing a line …

Evidence-based medicine–an appropriate tool for evidence-based health policy? A case study from Norway

K Malterud, AK Bjelland, KT Elvbakken - Health Research Policy and …, 2016 - Springer
Background Evidence-based policy (EBP), a concept modelled on the principles of evidence-
based medicine (EBM), is widely used in different areas of policymaking. Systematic reviews …

Avoiding methodological biases in meta-analysis

E Kaufmann, UD Reips, KM Merki - Zeitschrift für Psychologie, 2016 - econtent.hogrefe.com
Individual participant data (IPD) meta-analysis is the gold standard of meta-analyses. This
paper points out several advantages of IPD meta-analysis over classical meta-analysis …